arhgap21b

Ensembl ID:
ENSDARG00000075673
ZFIN ID:
ZDB-GENE-030131-4944
Description:
Novel protein similar to human and mouse Rho GTPase activating protein 21 (ARHGAP21) [Source:UniProt
Human Orthologue:
ARHGAP21
Human Description:
Rho GTPase activating protein 21 [Source:HGNC Symbol;Acc:23725]
Mouse Orthologue:
Arhgap21
Mouse Description:
Rho GTPase activating protein 21 Gene [Source:MGI Symbol;Acc:MGI:1918685]

Alleles

There are 3 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa19692 Nonsense Available for shipment Available now
sa32859 Nonsense Mutation detected in F1 DNA During 2016
sa32860 Essential Splice Site Mutation detected in F1 DNA During 2016

Mutation Details

Allele Name:
sa19692
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091298 Nonsense 449 1793 7 24
ENSDART00000134083 Nonsense 359 1703 4 21

The following transcripts of ENSDARG00000075673 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 12171140)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 12696365
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TCGTAGTGTGTCCTCTGATGGTCTCATACGGAAGCCCCGTGCTCATTCAT[C/A]AGACTATGTGGAACATGGTGAACTAGTTTCTGCTGCACCATGGGCAGCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32859
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091298 Nonsense 484 1793 7 24
ENSDART00000134083 Nonsense 394 1703 4 21

The following transcripts of ENSDARG00000075673 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 12171244)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 12696469
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TGGATAGGCAGCTTTATAGCAGAGTAGACCAGAGGAGTCGTCCCAGTAGA[C/T]AGTCTCTCCCACCAAGGGCGGTGCTTTACCGCCCACCAACAGGGTATGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32860
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091298 Essential Splice Site 1046 1793 None 24
ENSDART00000134083 Essential Splice Site 956 1703 None 21

The following transcripts of ENSDARG00000075673 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 12186884)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 12712109
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CACATTTGGAGTACGACTGGATAACTGCCCTCCTGCGCAAACCAATAAAG[T/C]AAGTGATTTAAACATGTCATTAGTTATGTTTTCATTAAAAAATGTGAATG
Associated Phenotype:
Not determined

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