MEGF6 (2 of 2)

Ensembl ID:
ENSDARG00000074808
Description:
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:3232]
Human Orthologue:
MEGF6
Human Description:
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:3232]
Mouse Orthologue:
Megf6
Mouse Description:
multiple EGF-like-domains 6 Gene [Source:MGI Symbol;Acc:MGI:1919351]

Alleles

There are 15 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa41912 Essential Splice Site Mutation detected in F1 DNA During 2016
sa3792 Nonsense Mutation detected in F1 DNA During 2016
sa24897 Essential Splice Site Mutation detected in F1 DNA During 2016
sa9346 Nonsense Mutation detected in F1 DNA During 2016
sa9355 Essential Splice Site Mutation detected in F1 DNA During 2016
sa19013 Essential Splice Site Mutation detected in F1 DNA During 2016
sa4437 Nonsense Mutation detected in F1 DNA During 2016
sa7679 Nonsense Mutation detected in F1 DNA During 2016
sa41911 Nonsense Mutation detected in F1 DNA During 2016
sa2600 Essential Splice Site Available for shipment Available now
sa15275 Essential Splice Site Available for shipment Available now
sa41910 Essential Splice Site Mutation detected in F1 DNA During 2016
sa15985 Nonsense Available for shipment Available now
sa21975 Essential Splice Site Available for shipment Available now
sa35153 Nonsense Mutation detected in F1 DNA During 2016

Mutation Details

Allele Name:
sa41912
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 296 1318 9 35
Genomic Location:
Chromosome 11 (position 42858860)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TGAATGTCATCCAGGTTATCAGCTCGCTGAAGACGGCAAGACATGTGAAG[G/A]TAAAATACACCTGCCTGTCTTATATTTTAAGATCACAGAGAGTTCTCAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3792
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Nonsense 301 1318 10 35
Genomic Location:
Chromosome 11 (position 42858722)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TTGGATGTGTTTATGCTGTGTGTTTTTGGTGCATYAGACATTGATGAGTG[T/A]GCGTYGGGTCAGACGGACTGTGCTCATGGCTGTCGTAACACCAGAGGATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24897
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 427 1318 12 35
Genomic Location:
Chromosome 11 (position 42857052)
KASP Assay ID:
554-7681.1 (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TACTGTACAGCCGGATATCGACTGAACACTGACGGATGCAGCTGTGATGG[T/C]AACACACATAAACTCACCAGGCCAGATTTTAAGAGAAGCTCATTACTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9346
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Nonsense 491 1318 15 35
Genomic Location:
Chromosome 11 (position 42850337)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
AACAAACAAMCMTGYGTGTGTGTCAGTGATGGAGGAGTCAGTGGAGGCGT[T/A]GAGCAGCGGTCAGACAGTCAATAAACCTGGACCAGGACCTCAGCTCRCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9355
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > T
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 539 1318 15 35
ENSDART00000109204 Essential Splice Site 539 1318 15 35
Genomic Location:
Chromosome 11 (position 42850190)
KASP Assay ID:
2260-4670.1 (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
GGACGACACTGGAGAACTGCKYGCYGAGAGCACTTTAGCTGAGAAATTCR[G/T]TGAGAAACCCTTTCCTTCTGTTCTGTAACACTGCKGGGATTTMATKTAYT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19013
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > T
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 539 1318 15 35
ENSDART00000109204 Essential Splice Site 539 1318 15 35
Genomic Location:
Chromosome 11 (position 42850190)
KASP Assay ID:
2260-4670.1 (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GGACGACACTGGAGAACTGCGTGCCGAGAGCACTTTAGCTGAGAAATTCA[G/T]TGAGAAACCCTTTCCTTCTGTTCTGTAACACTGCTGGGATTTCATTTACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa4437
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Nonsense 570 1318 16 35
Genomic Location:
Chromosome 11 (position 42849993)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TGTGAGGACTGTGTGAACGGAGGAGWGTGTAACAAACACAGAAATGCCTG[T/A]GACTGTCCTGACGGATGGACTGGAGTCGTCTGTAATGAGAGTGAGTTTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7679
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Nonsense 590 1318 17 35
Genomic Location:
Chromosome 11 (position 42849862)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TGTGAACCTGGACCACAACATCTTAACAGGATAGTTCACCYAAAAATRAA[C/T]AGTTCCTGTTAAAGGGCACCTATKGTGAAAAATCTACTTTTYAAGCTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41911
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Nonsense 725 1318 21 35
Genomic Location:
Chromosome 11 (position 42843406)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TATTTTGTCCCCCTAATAGAGTGTGAATCAGGGTTTTTTGGCTCTGCTTG[T/A]GAGAATAAATGCTCTTGTCCGCCTGGAGTGACCTGTGATCATGTGACTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2600
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 759 1318 21 35
Genomic Location:
Chromosome 11 (position 42843302)
KASP Assay ID:
554-2880.1 (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TTGTCAACCSAAATGTCCAGCTGGAAAAASAGGCGACAAATGTGACCAAG[G/C]TTTTTCAGAGTACTCATACACAACGTGTCTRTAGTTCATTATCTAAATTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15275
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 760 1318 21 35
Genomic Location:
Chromosome 11 (position 42843301)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TGTCAAMCSAAATGTCCAGCTGGAAAAASAGGCGACAAATGTGACCAAGS[T/A]TTTTCAGAGTACTCATACACAACGTGTCTRTAGTTCATTATCTAAATTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41910
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
A > T
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 804 1318 23 35
Genomic Location:
Chromosome 11 (position 42838134)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GCACGTCATGAATGTTACAGTATTTGTCATGTGTTTACGGAATCTGTCCC[A/T]GAATGCCCGGCTGGCTCGTTTGGGCCCGGCTGTAAGCATCGCTGCCAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15985
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Nonsense 962 1318 26 35
Genomic Location:
Chromosome 11 (position 42832266)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
AGATGTGAATGTGTGAATGGAGCTCAGTGTGATRGTCAGACGGGTSGCTG[T/A]GTTTGTCCGCCGGGCTGGRCAGGAGAGCGCTGTGAGAATGGTGAGCTCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21975
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Essential Splice Site 1019 1318 27 35
Genomic Location:
Chromosome 11 (position 42827191)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GGTCAGTGTCTCTGCCCTGCTGGATGGAGAGGAAGACGCTGTGAGAAAGG[T/C]CAGCTCATTAAAAAAAATCAAATATATATAATAAATGACTTTATAAATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35153
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109204 Nonsense 1233 1318 33 35
Genomic Location:
Chromosome 11 (position 42814861)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CGGATACAGGACAGTGTGTGTGTCCCGCTGGAGTCCACGGCCCGCGCTGT[C/T]AGCACGGTCAGACCTACAGTATATACATCAGTCAACACACACTTGAATAT
Associated Phenotype:
Not determined

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