tdp1

Ensembl ID:
ENSDARG00000073866
ZFIN ID:
ZDB-GENE-090909-1
Human Orthologue:
TDP1
Human Description:
tyrosyl-DNA phosphodiesterase 1 [Source:HGNC Symbol;Acc:18884]
Mouse Orthologue:
Tdp1
Mouse Description:
tyrosyl-DNA phosphodiesterase 1 Gene [Source:MGI Symbol;Acc:MGI:1920036]

Alleles

There are 3 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa42901 Nonsense Mutation detected in F1 DNA During 2016
sa23033 Nonsense Mutation detected in F1 DNA During 2016
sa6467 Nonsense Mutation detected in F1 DNA During 2016

Mutation Details

Allele Name:
sa42901
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108712 Nonsense 222 615 3 15
Genomic Location (Zv9):
Chromosome 17 (position 16260952)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 16411780
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TTTATTTAGTTTAATTACTGCTTTGACATCCCATGGATGGTGGAGCAGTA[T/A]CCGCCAGAATTTAGGTAGGATGAAATCTTTTAAATGTTCTTGCAGTGTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23033
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108712 Nonsense 392 615 9 15
Genomic Location (Zv9):
Chromosome 17 (position 16243934)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 16394762
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TTGCATGAACTCATTGTTTTTGTTTCCCTCAGTTGCTCAGCGAGCATACG[C/T]AACCCATGCAGAACGAAGAGCGATGGCACGTGCTTGGCCAGTTCTCCAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6467
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108712 Nonsense 478 615 11 15
Genomic Location (Zv9):
Chromosome 17 (position 16240941)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 16391769
KASP Assay ID:
554-5017.1 (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TCCCTTYAGCTGGAGGATCTTTACCTTACAGYATACAGACGGCACAAAAA[C/T]AGCTCTGGCTTCATTCTTACTTCCAGTAAGTTCTTYTTTCTCTTTCTCTG
Associated Phenotype:
Not determined

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