arfgef1

Ensembl ID:
ENSDARG00000063474
ZFIN ID:
ZDB-GENE-030131-108
Description:
Im:7138204 protein [Source:UniProtKB/TrEMBL;Acc:Q6DEJ1]
Human Orthologue:
ARFGEF1
Human Description:
ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) [Source:HGNC Sym
Mouse Orthologue:
Arfgef1
Mouse Description:
ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) Gene [Source:MGI

Alleles

There are 6 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa14568 Nonsense Available for shipment Available now
sa30078 Nonsense Mutation detected in F1 DNA During 2016
sa37862 Nonsense Mutation detected in F1 DNA During 2016
sa17540 Essential Splice Site Available for shipment Available now
sa778 Nonsense F2 line generated During 2016
sa10355 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa14568
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092783 Nonsense 692 1849 14 39
Genomic Location (Zv9):
Chromosome 24 (position 19336419)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 18642573
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TTAACTCTTTGGACTCCACTGCATCATCAGGCATTGGGAGCTACAGCACR[C/T]AGATGTCCGGAACAGACAACCCKGAGCAGTTTGAGGTCCTCAAACAACAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30078
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092783 Nonsense 825 1849 17 39
Genomic Location (Zv9):
Chromosome 24 (position 19332872)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 18639026
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GTTGCTAATTATGCTATAAACACTAAACTTGTCTCCCTTGTCTCCTTAGG[C/T]AAACACTGTTCGCCAGCGCTGACACCGCATACGTTCTTGCGTATTCAATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37862
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092783 Nonsense 884 1849 18 39
Genomic Location (Zv9):
Chromosome 24 (position 19332463)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 18638617
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GGTATCAATGACAGTAAAGATTTACCGGAGGAGTATCTCTCAGCCATTTA[T/A]GATGAAATCGCAGGGAAGAAAATCTCCATGAAGGAGACAAAGGAGTTAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17540
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092783 Essential Splice Site 958 1849 19 39
Genomic Location (Zv9):
Chromosome 24 (position 19330411)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 18636565
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
CCCCTTCACCAGCGCCACACATCTWGAGCATGTCAGACCAATGTTTAAGG[T/C]AWTCTCTTCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa778
Current Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092783 Nonsense 1167 1849 25 39
Genomic Location (Zv9):
Chromosome 24 (position 19321296)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 18627450
KASP Assay ID:
554-0683.1 (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
GATGGCTGTGCGCTGTCTCGATGGATGAACTGGCCTCCCCAACACACCCT[C/T]GAATGTTCAGTCTGCAGAAGATCGTGGAGATTTCATACTACAATATGGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10355
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092783 Nonsense 1611 1849 35 39
Genomic Location (Zv9):
Chromosome 24 (position 19301286)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 18607440
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
GCYTAATTTGATATTATGTTGTGTGTGTGCATTGTGCAGAAGCTCAGGAA[C/T]AGAGGCTGTTTGCTGCGCTACTCATYAAGTGTGTGGTTCAGCTGGAGCTC
Associated Phenotype:
Not determined

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