ihha

Ensembl ID:
ENSDARG00000058733
ZFIN ID:
ZDB-GENE-051010-1
Description:
Indian hedgehog homolog a [Source:RefSeq peptide;Acc:NP_001030165]
Human Orthologue:
IHH
Human Description:
Indian hedgehog [Source:HGNC Symbol;Acc:5956]
Mouse Orthologue:
Ihh
Mouse Description:
Indian hedgehog Gene [Source:MGI Symbol;Acc:MGI:96533]

Alleles

There are 3 alleles of this gene:

Allele name Consequence Status Availability Estimate
hu2131 Nonsense Available for shipment Available now
sa30645 Nonsense Mutation detected in F1 DNA During 2016
sa34554 Nonsense Mutation detected in F1 DNA During 2016

Mutation Details

Allele Name:
hu2131
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081660 Nonsense 44 413 1 3
Genomic Location:
Chromosome 9 (position 7400713)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
AGGGGACATGGGAAAAGGCGGCCTCCGAAGAAACTGACACCCCTTAATTA[C/A]AAGCAGTTTAGTCCAAATGTAGCCGAGAAGACACTGGGAGCCAGCGGGAG
Associated Phenotype:

Normal

Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461

Mutation Details

Allele Name:
sa30645
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081660 Nonsense 361 413 3 3
Genomic Location:
Chromosome 9 (position 7408594)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
ATTGTTTCCTCCTGCTACGCAGCCGTGGACCAGCACTGGCTGGCTCACTG[G/A]GCTTTCGGGCCACTCAGGGTACTTTATAACTGGGGAGGTCCTGTTGGACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34554
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081660 Nonsense 392 413 3 3
Genomic Location:
Chromosome 9 (position 7408687)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GTTGGACATCAAGTCACAGGGATACACTGGTATTCCTCATTGCTTCACTG[G/A]ATCGGAACTCAAGTGCTCGATCCAGCACACTTCCATCCTTGGAGCATGAT
Associated Phenotype:
Not determined

GWAS

This gene's human homologue has been identified in the following GWAS studies:

  • Height: A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. (View Study)
  • Height: Genome-wide association analysis identifies 20 loci that influence adult height. (View Study)
  • Height: Hundreds of variants clustered in genomic loci and biological pathways affect human height. (View Study)
  • Height: Many sequence variants affecting diversity of adult human height. (View Study)

(GWAS data comes from http://www.genome.gov/gwastudies/.)

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

Short-link