araf

Ensembl ID:
ENSDARG00000054533
ZFIN ID:
ZDB-GENE-050102-2
Description:
serine/threonine-protein kinase A-Raf [Source:RefSeq peptide;Acc:NP_991306]
Human Orthologue:
ARAF
Human Description:
v-raf murine sarcoma 3611 viral oncogene homolog [Source:HGNC Symbol;Acc:646]
Mouse Orthologue:
Araf
Mouse Description:
v-raf murine sarcoma 3611 viral oncogene homolog Gene [Source:MGI Symbol;Acc:MGI:88065]

Alleles

There are 7 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa30859 Nonsense Mutation detected in F1 DNA During 2016
sa40437 Nonsense Mutation detected in F1 DNA During 2016
sa13556 Nonsense Available for shipment Available now
sa20425 Nonsense Available for shipment Available now
sa33608 Nonsense Mutation detected in F1 DNA During 2016
sa31438 Essential Splice Site Available for shipment Available now
sa31439 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa30859
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076687 Nonsense 10 605 1 17
ENSDART00000076696 Nonsense 10 604 1 17
ENSDART00000136342 Nonsense 10 265 1 6
ENSDART00000138182 Nonsense 10 608 1 15
ENSDART00000140081 Nonsense 10 604 1 15
ENSDART00000076687 Nonsense 10 605 1 17
ENSDART00000076696 Nonsense 10 604 1 17
ENSDART00000136342 Nonsense 10 265 1 6
ENSDART00000138182 Nonsense 10 608 1 15
ENSDART00000140081 Nonsense 10 604 1 15
Genomic Location (Zv9):
Chromosome 5 (position 28500926)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26256224
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TCACTGCCCCATCGGAGACACCATGTCCAACACTTCCTCCTGTTCCTCCT[C/A]GGGGGAAACCAGCCCGGACGATACACCCCGAGGTGGAGGCACCATCCGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40437
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076687 Nonsense 10 605 1 17
ENSDART00000076696 Nonsense 10 604 1 17
ENSDART00000136342 Nonsense 10 265 1 6
ENSDART00000138182 Nonsense 10 608 1 15
ENSDART00000140081 Nonsense 10 604 1 15
ENSDART00000076687 Nonsense 10 605 1 17
ENSDART00000076696 Nonsense 10 604 1 17
ENSDART00000136342 Nonsense 10 265 1 6
ENSDART00000138182 Nonsense 10 608 1 15
ENSDART00000140081 Nonsense 10 604 1 15
Genomic Location (Zv9):
Chromosome 5 (position 28500926)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26256224
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TCACTGCCCCATCGGAGACACCATGTCCAACACTTCCTCCTGTTCCTCCT[C/A]GGGGGAAACCAGCCCGGACGATACACCCCGAGGTGGAGGCACCATCCGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13556
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076687 Nonsense 46 605 2 17
ENSDART00000076696 Nonsense 46 604 2 17
ENSDART00000136342 Nonsense 46 265 2 6
ENSDART00000138182 Nonsense 46 608 2 15
ENSDART00000140081 Nonsense 46 604 2 15
Genomic Location (Zv9):
Chromosome 5 (position 28501153)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26256451
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
CCCATCTTTGATTATGTTCAGGYAAACGTTCGGCCTGGGCAAACTGTGTA[T/G]GATAGTTTAGATAAAGCCCTAAAAGTCMGWGGCCTAAGCCARGATTGCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20425
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076687   None 605 None 17
ENSDART00000076696   None 604 None 17
ENSDART00000136342 Nonsense 263 265 6 6
ENSDART00000138182   None 608 None 15
ENSDART00000140081   None 604 None 15
Genomic Location (Zv9):
Chromosome 5 (position 28502798)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26258096
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CAAATCCACATCTCTTGATGTTCTCTCATTTTGACATTGTTTTAAAGGAA[C/T]AGTTCGCTTAAACATTATAGTCACTCTCAATGTTTTCTACTAAATCCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33608
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076687 Nonsense 282 605 8 17
ENSDART00000076696 Nonsense 278 604 8 17
ENSDART00000136342   None 265 None 6
ENSDART00000138182 Nonsense 282 608 8 15
ENSDART00000140081 Nonsense 278 604 8 15
Genomic Location (Zv9):
Chromosome 5 (position 28503760)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26259058
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TAGGGTCGCCAGGAAGAAAACCCCCCAAATCCCCTTCTGAACCCAAGGAA[C/T]GAAAGCAGTCCTCGTCTGATGATAAAAAGAAAGTGGTGTGTTTTTATTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31438
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076687 Essential Splice Site 361 605 9 17
ENSDART00000076696 Essential Splice Site 357 604 9 17
ENSDART00000136342   None 265 None 6
ENSDART00000138182 Essential Splice Site 361 608 9 15
ENSDART00000140081 Essential Splice Site 357 604 9 15
Genomic Location (Zv9):
Chromosome 5 (position 28504103)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26259401
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CCACACCGGAGCAGCTCCAGGCCTTTAAAAATGAGATGCAGGTTTTACGG[T/G]GAGTCGTCAGTGGGATTTAGAGCTTCACAGAACATCTTTGATCATTAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31439
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076687 Nonsense 592 605 17 17
ENSDART00000076696 Nonsense 591 604 15 17
ENSDART00000136342   None 265 None 6
ENSDART00000138182 Nonsense 595 608 15 15
ENSDART00000140081 Nonsense 591 604 15 15
Genomic Location (Zv9):
Chromosome 5 (position 28509010)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26264308
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
AAATCGAGCGGAGTGCCTCTGAGCCCTCTCTACACCGTGCTGTACATGCC[G/T]AGGACCTGAATCCGCTTCTCCTTCACACCACGCGCTTCCTGTGAGACTCC
Associated Phenotype:
Not determined

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