tas1r2.1

Ensembl ID:
ENSDARG00000053135
ZFIN ID:
ZDB-GENE-070917-1
Description:
taste receptor, type 1, member 2.1 [Source:RefSeq peptide;Acc:NP_001034920]
Human Orthologue:
TAS1R2
Human Description:
taste receptor, type 1, member 2 [Source:HGNC Symbol;Acc:14905]
Mouse Orthologue:
Tas1r2
Mouse Description:
taste receptor, type 1, member 2 Gene [Source:MGI Symbol;Acc:MGI:1933546]

Alleles

There are 2 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa12214 Essential Splice Site Available for shipment Available now
sa21376 Nonsense Mutation detected in F1 DNA During 2016

Mutation Details

Allele Name:
sa12214
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000075125 Essential Splice Site 160 825 2 6
Genomic Location (Zv9):
Chromosome 8 (position 48742033)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 46580291
GRCz10 8 46597939
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
ACGGACTATTTCAATAGCACCACTGATCACAATGGACCTTATACCRTTGG[T/C]AAATCTTGTACARTTTACNNATATACAAMATGCTAAATWAATMATTTTWA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21376
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000075125 Nonsense 292 825 3 6
Genomic Location (Zv9):
Chromosome 8 (position 48742500)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 46580758
GRCz10 8 46598406
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GCCATAGCGGACAACATCCGAGACAAAGTATGGATTGCGAGTGAAACCTG[G/A]TCTATGAATCAACAGCTTCCAAGGGAGCCAGGAGTTGAGAAAATCGGAAC
Associated Phenotype:
Not determined

GWAS

This gene's human homologue has been identified in the following GWAS studies:

  • Parkinson's disease: Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. (View Study)

(GWAS data comes from http://www.genome.gov/gwastudies/.)

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

Short-link