tpra

Ensembl ID:
ENSDARG00000052914
ZFIN ID:
ZDB-GENE-081104-2
Description:
Novel protein similar to vertebrate translocated promoter region (To activated MET oncogene) (TPR) [
Human Orthologue:
TPR
Human Description:
translocated promoter region (to activated MET oncogene) [Source:HGNC Symbol;Acc:12017]
Mouse Orthologue:
Tpr
Mouse Description:
translocated promoter region Gene [Source:MGI Symbol;Acc:MGI:1922066]

Alleles

There are 4 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa10563 Nonsense Available for shipment Available now
sa2072 Essential Splice Site Mutation detected in F1 DNA During 2014
sa19727 Nonsense Available for shipment Available now
sa25104 Essential Splice Site Mutation detected in F1 DNA During 2014

Mutation Details

Allele Name:
sa10563
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027144 None None 366 None 11
ENSDART00000074850 None None 1309 None 28
ENSDART00000111541 Nonsense 92 1274 3 28
ENSDART00000142968 None None 198 None 6
Genomic Location:
Chromosome 2 (position 20660889)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
ATAACATGATTGCGTGTGTTTTGATTGTTAAGTGGAAGAGCTTAAGAAGT[T/G]AAAAGAGATAGAAGAAGTGCAGGGAACAAYGCAAGAGGTAACTATTTGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2072
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
G > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027144 None None 366 None 11
ENSDART00000074850 None None 1309 None 28
ENSDART00000111541 Essential Splice Site 171 1274 5 28
ENSDART00000142968 None None 198 None 6
Genomic Location:
Chromosome 2 (position 20660233)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
AGCTCCAGCTTAAACTAGATGAACTTCAGTCTTCTGARGTTTCCATTCAG[G/A]TAAGCAGGGACTTTCATTCAGCTCTGTCTACAACAAATTAAAGGCATCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19727
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027144 None None 366 None 11
ENSDART00000074850 None None 1309 None 28
ENSDART00000111541 Nonsense 439 1274 12 28
ENSDART00000142968 None None 198 None 6
Genomic Location:
Chromosome 2 (position 20645256)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CTGGAGGTGGAAACCAAAGCTCCCATCCTGAAACGCCAGAGAGAGGAATA[T/G]GAGAGCATGCAGAAGTCTATGACCAGTCTCTGTTATAAACTAGAGCAAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25104
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
G > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027144 None None 366 None 11
ENSDART00000074850 None None 1309 None 28
ENSDART00000111541 Essential Splice Site 458 1274 12 28
ENSDART00000142968 None None 198 None 6
Genomic Location:
Chromosome 2 (position 20645198)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
TGCAGAAGTCTATGACCAGTCTCTGTTATAAACTAGAGCAAGCTATGAAG[G/A]TTTGCACACATTTGAGAGCTAATGCAAAAAGAAGGAACAGGATAATGATG
Associated Phenotype:
Not determined

Register

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* quick link - http://q.sanger.ac.uk/u05rn3qm