fas

Ensembl ID:
ENSDARG00000043586
ZFIN ID:
ZDB-GENE-061019-2
Description:
Fas [Source:UniProtKB/TrEMBL;Acc:Q0PKX5]
Human Orthologue:
FAS
Human Description:
Fas (TNF receptor superfamily, member 6) [Source:HGNC Symbol;Acc:11920]
Mouse Orthologues:
Fas, Tnfrsf22, Tnfrsf23, Tnfrsf26
Mouse Descriptions:
Fas (TNF receptor superfamily member 6) Gene [Source:MGI Symbol;Acc:MGI:95484]
tumor necrosis factor receptor superfamily, member 22 Gene [Source:MGI Symbol;Acc:MGI:1930270]
tumor necrosis factor receptor superfamily, member 23 Gene [Source:MGI Symbol;Acc:MGI:1930269]
tumor necrosis factor receptor superfamily, member 26 Gene [Source:MGI Symbol;Acc:MGI:2651928]

Alleles

There are 2 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa11234 Essential Splice Site Available for shipment Available now
sa4712 Essential Splice Site Mutation detected in F1 DNA During 2014

Mutation Details

Allele Name:
sa11234
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079563 Essential Splice Site 13 293 1 8
Genomic Location:
Chromosome 17 (position 23461122)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
CCTCCTCGAGATGTTTGTTTGCAAATTCGGCGTTTTTATCGTCTTTGTGG[T/G]GAGTAAGTCTTTGTATTRTTCAGCTTTATGTAGTRTTTTTTAGGAGAAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa4712
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079563 Essential Splice Site 47 293 2 8
Genomic Location:
Chromosome 17 (position 23459249)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TTTGGAACTTACCAGCATGAGAGGAACACATGTTGCCTCTGTCCTGCAGG[T/C]AAGATAATGCATAACTTATTATGCATACAGAACTACCCCGATGTTCCTCA
Associated Phenotype:
Not determined

GWAS

This gene's human homologue has been identified in the following GWAS studies:

(GWAS data comes from http://www.genome.gov/gwastudies/.)

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

* quick link - http://q.sanger.ac.uk/s6ztv6uk