mars

Ensembl ID:
ENSDARG00000034396
ZFIN ID:
ZDB-GENE-030219-83
Description:
methionyl-tRNA synthetase, cytoplasmic [Source:RefSeq peptide;Acc:NP_956370]
Human Orthologue:
MARS
Human Description:
methionyl-tRNA synthetase [Source:HGNC Symbol;Acc:6898]
Mouse Orthologue:
Mars
Mouse Description:
methionine-tRNA synthetase Gene [Source:MGI Symbol;Acc:MGI:1345633]

Alleles

There are 5 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa33988 Essential Splice Site Mutation detected in F1 DNA During 2016
sa40815 Essential Splice Site Mutation detected in F1 DNA During 2016
sa40814 Essential Splice Site Mutation detected in F1 DNA During 2016
sa7590 Missense Mutation detected in F1 DNA During 2016
sa16933 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa33988
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 35 922 None 22
ENSDART00000074544 Essential Splice Site 35 913 None 21
ENSDART00000144514 Essential Splice Site 64 942 None 21
ENSDART00000144911 Essential Splice Site 64 951 None 22
Genomic Location (Zv9):
Chromosome 6 (position 58877375)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58980503
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CTGGAGCTCAGCGGAGTCCGGTGTGAAACTCAGCTGGTGAAACACGAGGG[T/C]GAGTGTGGAGGAAAGTGTGTGTGTGTGTGCCGTGTGGGATTGTGAAGTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40815
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 91 922 3 22
ENSDART00000074544 Essential Splice Site 91 913 3 21
ENSDART00000144514 Essential Splice Site 120 942 3 21
ENSDART00000144911 Essential Splice Site 120 951 3 22
Genomic Location (Zv9):
Chromosome 6 (position 58866869)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58969997
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GACAGACGCGACAAACCAGTGGCTGGAATGGGAGGCTACAAATTTACAGG[T/C]GACGATTATTACATTGCACAACATTAAAATAACTTTAGATAGTTAACATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40814
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > T
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 430 922 11 22
ENSDART00000074544 Essential Splice Site 430 913 11 21
ENSDART00000144514 Essential Splice Site 459 942 11 21
ENSDART00000144911 Essential Splice Site 459 951 11 22
Genomic Location (Zv9):
Chromosome 6 (position 58852038)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58955166
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
ATTATTAAATTGAACAATAACATTGTGTGTGTGTGTGTGTGTGTCCTGCA[G/T]AATCCTCAGTGTAAGGTGTGTAAGGAGACGCCGGTGATTCGCTCCTCCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7590
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2016.
Mutation:
G > A
Consequence:
Missense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Missense 495 922 12 22
ENSDART00000074544 Missense 495 913 12 21
ENSDART00000144514 Missense 524 942 12 21
ENSDART00000144911 Missense 524 951 12 22
Genomic Location (Zv9):
Chromosome 6 (position 58851579)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58954707
KASP Assay ID:
554-4254.1 (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
CATCACTCGCTCCTGGCTGCGGGACGGTCTGAAGCCGCGCTGCATCACAC[G/A]TGACTTRAAGTGGGGGACGCCGGTGCCGCACCCCGACTACAAGGAGAAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16933
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049574 Essential Splice Site 822 922 19 22
ENSDART00000074544 Essential Splice Site 822 913 19 21
ENSDART00000144514 Essential Splice Site 851 942 19 21
ENSDART00000144911 Essential Splice Site 851 951 19 22
Genomic Location (Zv9):
Chromosome 6 (position 58833973)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58937101
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
GGAGAAYGAGCAGATCGAGGCTCTGAGGAAGAGATTCGGAGGACTGCAGG[T/C]TTGTAAAGACGTGCATTATTAAYCAGGGCCACAAGAAGRAAATCTGATTT
Associated Phenotype:
Not determined

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

Short-link