tada2a

Ensembl ID:
ENSDARG00000031562
ZFIN ID:
ZDB-GENE-060929-508
Description:
transcriptional adapter 2-alpha [Source:RefSeq peptide;Acc:NP_001070609]
Human Orthologue:
TADA2A
Human Description:
transcriptional adaptor 2A [Source:HGNC Symbol;Acc:11531]
Mouse Orthologue:
Tada2a
Mouse Description:
transcriptional adaptor 2A Gene [Source:MGI Symbol;Acc:MGI:2144471]

Alleles

There is 1 allele of this gene:

Allele name Consequence Status Availability Estimate
sa22601 Nonsense Mutation detected in F1 DNA During 2014

Mutation Details

Allele Name:
sa22601
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000090939 Nonsense 118 421 5 14
ENSDART00000130670 Nonsense 118 445 5 15
Genomic Location:
Chromosome 15 (position 14809958)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
ATGCGCTCTAAAACCAAAGAAGAATGTGAAGGTCACTACATGAAGAACTA[T/A]ATCAACAATCCTCTGTTCTCCTCCACTCTGCTCAGTCTCAGACATATGGA
Associated Phenotype:
Not determined

GWAS

This gene's human homologue has been identified in the following GWAS studies:

  • Ovarian cancer: GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. (View Study)

(GWAS data comes from http://www.genome.gov/gwastudies/.)

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

* quick link - http://q.sanger.ac.uk/s04hk6zq