TIAM1 (1 of 2)

Ensembl ID:
ENSDARG00000025920
Description:
T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:11805]
Human Orthologue:
TIAM1
Human Description:
T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:11805]
Mouse Orthologue:
Tiam1
Mouse Description:
T-cell lymphoma invasion and metastasis 1 Gene [Source:MGI Symbol;Acc:MGI:103306]

Alleles

There are 2 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa10824 Essential Splice Site Available for shipment Available now
sa24996 Nonsense Mutation detected in F1 DNA During 2014

Mutation Details

Allele Name:
sa10824
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089694 Essential Splice Site 1175 1562 21 27
Genomic Location:
Chromosome 15 (position 41068898)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TGGCTCATGATACCTGACTGCTATTTGATCTCTCCTCTCTGCTGTGTGCA[G/A]TTGCAATGAAAGCCATGAACACAGTGGCCAGCCACATCAATGAGATGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24996
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000089694 Nonsense 1547 1562 27 27
Genomic Location:
Chromosome 15 (position 41079508)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CTGTGGCCAGCGTTGACGAGCAAGCGACATCTGATGATGTTGTCTGGGTG[C/T]GACGGGACAGCGGTGCAGAGAACGAGACACAGGACGAAAGCCAGAGCTGA
Associated Phenotype:
Not determined

GWAS

This gene's human homologue has been identified in the following GWAS studies:

  • Renal sinus fat : Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study. (View Study)

(GWAS data comes from http://www.genome.gov/gwastudies/.)

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

* quick link - http://q.sanger.ac.uk/u4k2zuz3