brd8

Ensembl ID:
ENSDARG00000025071
ZFIN ID:
ZDB-GENE-030722-10
Description:
Bromodomain containing 8 [Source:UniProtKB/TrEMBL;Acc:Q6PFM2]
Human Orthologue:
BRD8
Human Description:
bromodomain containing 8 [Source:HGNC Symbol;Acc:19874]
Mouse Orthologues:
4933408B17Rik, Brd8
Mouse Descriptions:
bromodomain containing 8 Gene [Source:MGI Symbol;Acc:MGI:1925906]
RIKEN cDNA 4933408B17 gene Gene [Source:MGI Symbol;Acc:MGI:3045347]

Alleles

There are 3 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa265 Nonsense Confirmed mutation in F2 line During 2014
sa15090 Essential Splice Site Available for shipment Available now
sa3905 Nonsense Mutation detected in F1 DNA During 2014

Mutation Details

Allele Name:
sa265
Current Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
G > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028623 Nonsense 443 840 13 19
ENSDART00000123139 Nonsense 452 849 13 19

The following transcripts of ENSDARG00000025071 do not overlap with this mutation:

Genomic Location:
Chromosome 14 (position 7685694)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
CTCCCTCTGTGAGGATCCAGCAGTCGGAGGTCACCCCCTCACCAGCCCCT[G/A]GGAATCACAGACATTTAAGGCAGCCGAACCAGAGCCTATGATCCAGCAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15090
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028623 Essential Splice Site 574 840 13 19
ENSDART00000123139 Essential Splice Site 583 849 13 19

The following transcripts of ENSDARG00000025071 do not overlap with this mutation:

Genomic Location:
Chromosome 14 (position 7686089)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
YWCCCTGTCTGGATTCAGAAGATAGCTCGGCCTCAGCAAAAGATGYAAAG[G/A]TATYAGCAAAGCAAAAKGAAAAGTATGCCTTTATGTACAATGCTRWTCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3905
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
C > T
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028623 Nonsense 816 840 18 19
ENSDART00000123139 Nonsense 825 849 18 19

The following transcripts of ENSDARG00000025071 do not overlap with this mutation:

Genomic Location:
Chromosome 14 (position 7697872)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
CTCATTTAGAGCCAGAACCACCAGCCAGAAGGAAAAGGAACAACTCCAAA[C/T]AAGACACTGTTGAGAAGGTCAGTGTTGTMCACACACAAACATACACTCAA
Associated Phenotype:
Not determined

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

* quick link - http://q.sanger.ac.uk/08iyf3zq