Knockout List

The following genes (beginning with I) have all been mutated. 24459 alleles have currently been generated. A list of genes with alleles available to order is also available.

Gene name Ensembl ID Human orthologue Mouse orthologue Alleles found Associated phenotype
iars ENSDARG00000007955 IARS Iars 1 Not determined
iars2 ENSDARG00000044134 IARS2 Iars2 3 Not determined
IBTK ENSDARG00000074424 IBTK Ibtk 3 Not determined
ica ENSDARG00000057688 ICA1L Ica1l 1 Not determined
ICA1 ENSDARG00000042608 ICA1 Ica1 1 Not determined
icmt ENSDARG00000020241 ICMT Icmt 1 Not determined
icn ENSDARG00000009978 S100P None 1 Not determined
id2b ENSDARG00000029544 ID2 Id2 1 Not determined
ide ENSDARG00000075570 IDE Ide 1 Not determined
IDH2 ENSDARG00000003795 IDH2 Idh2 1 Not determined
idh3g ENSDARG00000023648 IDH3G Idh3g 1 Not determined
ido1 ENSDARG00000033594 IDO2 Ido2 1 Not determined
idua ENSDARG00000062904 IDUA Idua 1 Not determined
ier5 ENSDARG00000009881 IER5 Ier5 1 Normal
ifi30 ENSDARG00000056378 IFI30 Ifi30 2 Not determined
ifih1 ENSDARG00000018553 IFIH1 Ifih1 1 Not determined
ifit2 ENSDARG00000043584 IFIT5
IFIT1
IFIT1B
IFIT3
IFIT2
Ifit1
Ifit2
2010002M12Rik
Gm14446
Ifit3
I830012O16Rik
2 Not determined
ifng1-1 ENSDARG00000045671 None None 3 Normal
ifng1-2 ENSDARG00000024211 None None 2 Not determined
ifnphi1 ENSDARG00000025607 None None 1 Not determined
ifnphi4 ENSDARG00000090603 None None 1 Not determined
ifrd2 ENSDARG00000036811 IFRD2 Ifrd2 2 Not determined
ift140 ENSDARG00000031886 IFT140 Ift140 3 Not determined
ift172 ENSDARG00000041870 IFT172 Ift172 1 Not determined
ift80 ENSDARG00000038879 IFT80
RP11-432B6.3
Ift80 2 Not determined
ift81 ENSDARG00000007444 IFT81 Ift81 3 Not determined
ift88 ENSDARG00000027234 IFT88 Ift88 3 Not determined
igdcc4 ENSDARG00000076919 IGDCC4 Igdcc4 1 Not determined
igf1ra ENSDARG00000027423 IGF1R Igf1r 1 Not determined
igf1rb ENSDARG00000034434 IGF1R Igf1r 5 Not determined
igf2bp1 ENSDARG00000061478 IGF2BP1 Igf2bp1 3 Not determined
igf2bp2a ENSDARG00000003421 IGF2BP2 Igf2bp2 1 Not determined
igf2bp2b ENSDARG00000061661 IGF2BP2 Igf2bp2 2 Not determined
igf2bp3 ENSDARG00000010266 IGF2BP3 Igf2bp3 1 Not determined
igf2r ENSDARG00000006094 IGF2R Igf2r 4 Not determined
igfbp2b ENSDARG00000031422 IGFBP2 Igfbp2 1 Not determined
igfbp3 ENSDARG00000014859 IGFBP3 Igfbp3 1 Not determined
IGFN1 (3 of 3) ENSDARG00000086028 IGFN1 Igfn1 4 Not determined
IGFN1 (2 of 3) ENSDARG00000075926 IGFN1 Igfn1 1 Not determined
ighmbp2l ENSDARG00000069274 IGHMBP2 Ighmbp2 3 Not determined
igsf21a ENSDARG00000031049 IGSF21 Igsf21 2 Not determined
igsf21b ENSDARG00000056084 IGSF21 Igsf21 1 Not determined
IGSF5 (2 of 2) ENSDARG00000090953 IGSF5 Igsf5 1 Not determined
igsf9ba ENSDARG00000033845 IGSF9B Igsf9b 2 Not determined
ihha ENSDARG00000058733 IHH Ihh 1 Normal
ihhb ENSDARG00000058815 IHH Ihh 1 Not determined
ikbke ENSDARG00000070606 IKBKE Ikbke 1 Not determined
ikbkg ENSDARG00000017037 IKBKG Ikbkg 1 Not determined
ikzf1 ENSDARG00000013539 IKZF1 Ikzf1 3 Not determined
ikzf5 ENSDARG00000056491 IKZF5 Ikzf5 2 Normal
il10 ENSDARG00000078147 IL10 Il10 3 Normal
il11b ENSDARG00000058557 IL11 Il11 1 Not determined
il11ra ENSDARG00000026736 IL11RA Il11ra1
Gm2002
Il11ra2
Gm13305
1 Not determined
il12ba ENSDARG00000033727 IL12B Il12b 1 Not determined
il13ra1 ENSDARG00000080020 None None 1 Not determined
il13ra2 ENSDARG00000039436 IL13RA2
IL5RA
IL13RA1
Il13ra2
Il5ra
Il13ra1
3 Not determined
il17c ENSDARG00000057180 IL17C
IL25
Il17c
Il25
1 Not determined
il17d ENSDARG00000010700 IL17D Il17d 1 Not determined
IL17RA (4 of 4) ENSDARG00000089153 IL17RA Il17ra 2 Not determined
IL17REL ENSDARG00000089131 IL17REL None 1 Not determined
il1b ENSDARG00000005419 IL1B Il1b 2 Not determined
IL1RAP ENSDARG00000091088 IL1RAP Il1rap 2 Not determined
il1rapl1a ENSDARG00000062045 IL1RAPL1 Il1rapl1 6 Not determined
il1rapl1b ENSDARG00000078740 IL1RAPL1 Il1rapl1 1 Not determined
il1rapl2 ENSDARG00000037553 IL1RAPL2 Il1rapl2 3 1 phenotype
il1rl ENSDARG00000068609 None None 1 Not determined
il21r ENSDARG00000069961 IL21R Il21r 1 Not determined
il23r ENSDARG00000052158 IL12RB2 Il12rb2 1 Not determined
il2rb ENSDARG00000075720 IL2RB Il2rb 4 Not determined
il2rgb ENSDARG00000053702 IL2RG Il2rg 1 Not determined
il4r ENSDARG00000031051 None None 1 Not determined
il6st ENSDARG00000030498 IL6ST Il6st 4 Normal
ildr2 ENSDARG00000014180 ILDR2 Ildr2 3 Not determined
ilf3a ENSDARG00000058660 ILF3 Ilf3 2 Not determined
ilvbl ENSDARG00000017126 ILVBL Ilvbl 2 Not determined
im:6893790 ENSDARG00000073797 RRN3
RRN3P2
RRN3P3
AC092375.1
Rrn3 1 Not determined
im:6903726 ENSDARG00000070673 PTGR2 Ptgr2 2 Not determined
im:6904866 ENSDARG00000070743 TMEM45A Tmem45a
2310005G13Rik
1 Not determined
im:6907121 ENSDARG00000060282 RNF121 Rnf121 1 Not determined
im:7136778 ENSDARG00000058470 MAPK13 Mapk13 1 Not determined
im:7137453 ENSDARG00000077318 C10orf140
C17orf96
2810030E01Rik
E130012A19Rik
1 Not determined
im:7138144 ENSDARG00000031108 LRBA Lrba 1 Normal
im:7138239 ENSDARG00000039070 None None 2 Not determined
im:7138263 ENSDARG00000056247 C16orf79 9930021D14Rik 1 Not determined
im:7138629 ENSDARG00000028056 KNTC1 Kntc1 3 Not determined
im:7140212 ENSDARG00000062113 LRRC8D Lrrc8d 1 Not determined
im:7142760 ENSDARG00000054032 RAB24 Rab24 2 Not determined
im:7143453 ENSDARG00000042126 ELMO3 Elmo3 1 Not determined
im:7143718 ENSDARG00000070717 SLC25A18 Slc25a18 2 Not determined
im:7143923 ENSDARG00000037926 CPNE8 Cpne8 1 Not determined
im:7145024 ENSDARG00000089139 C11orf74 B230118H07Rik 1 Not determined
im:7145112 ENSDARG00000034060 ELAC2 Elac2 4 Not determined
im:7145391 ENSDARG00000086747 TOLLIP Tollip 4 Normal
im:7145503 ENSDARG00000016491 AGL Agl 4 Not determined
im:7147241 ENSDARG00000052046 SEC16B Sec16b 5 Not determined
im:7147678 ENSDARG00000003313 EPS8L1 Eps8l1 2 Not determined
im:7147988 ENSDARG00000076868 STARD13 Stard13 2 Not determined
im:7149048 ENSDARG00000076870 FAM38A Fam38a 6 Not determined
im:7150991 ENSDARG00000074617 WFS1 Wfs1 4 Not determined
im:7153552 ENSDARG00000054707 DHX8 Dhx8 4 Not determined
im:7154842 ENSDARG00000052917 CAPN14
CAPN13
Capn13 2 Not determined
im:7154960 ENSDARG00000060442 C19orf6 ORF61 2 Not determined
im:7155895 ENSDARG00000062947 AMN Amn 1 Not determined
im:7158374 ENSDARG00000061844 ARHGEF15 Arhgef15 2 Not determined
im:7159098 ENSDARG00000018847 UTP20 Utp20 6 Not determined
im:7160995 ENSDARG00000077227 FBXL6 Fbxl6 1 Not determined
im:7162646 ENSDARG00000014378 SLC12A4 Slc12a4 3 Not determined
im:7162965 ENSDARG00000018345 DAPK2 Dapk2 3 Not determined
im:7163548 ENSDARG00000062267 KDM3B
KDM3A
Kdm3b
Kdm3a
4 Not determined
im:7163673 ENSDARG00000086764 MDC1 Mdc1 2 Not determined
im:7165241 ENSDARG00000002494 ITGB6 Itgb6 1 Not determined
immp1l ENSDARG00000045935 IMMP1L Immp1l 2 Normal
immp2l ENSDARG00000004925 IMMP2L Immp2l 1 Not determined
immt ENSDARG00000057454 IMMT Immt 1 Not determined
imp3 ENSDARG00000069287 IMP3 Imp3 1 Not determined
impa1 ENSDARG00000003517 IMPA1 Impa1 1 Not determined
impdh1a ENSDARG00000042336 IMPDH1 Impdh1 5 Not determined
impdh2 ENSDARG00000006900 IMPDH2 Impdh2 1 Not determined
IMPG2 (3 of 4) ENSDARG00000088751 IMPG2 Impg2 1 Not determined
inaa ENSDARG00000011862 INA Ina 1 Not determined
inadl ENSDARG00000024964 INADL Inadl 6 Normal
ing3 ENSDARG00000034326 ING3 Ing3 6 1 phenotype
ing5a ENSDARG00000022413 ING5 Ing5 1 Normal
inhbab ENSDARG00000024759 INHBA Inhba 2 Normal
inhbb ENSDARG00000040777 INHBB Inhbb 1 Not determined
ino80da ENSDARG00000078199 INO80D Ino80d 2 Not determined
inpp4a ENSDARG00000063352 INPP4A Inpp4a 2 Not determined
inpp5f ENSDARG00000061437 INPP5F Inpp5f 6 Not determined
inpp5ja ENSDARG00000078542 INPP5J Inpp5j 1 Not determined
inppl1a ENSDARG00000030146 INPPL1 Inppl1 3 Not determined
inppl1b ENSDARG00000001442 INPPL1 Inppl1 2 Not determined
insl3 ENSDARG00000035862 None None 1 Not determined
insm1a ENSDARG00000091756 INSM1 Insm1 1 Not determined
insm1b ENSDARG00000053301 INSM1 Insm1 1 Not determined
insra ENSDARG00000011948 INSR Insr 2 Normal
insrb ENSDARG00000071524 INSR Insr 2 Not determined
INT3_DANRE ENSDARG00000016811 INTS3 Ints3 3 Not determined
ints1 ENSDARG00000059631 INTS1 Ints1 4 Not determined
ints2 ENSDARG00000069085 INTS2 Ints2 2 Not determined
ints6 ENSDARG00000013025 INTS6 Ints6 2 Not determined
ints7 ENSDARG00000019300 INTS7 Ints7 2 Not determined
ints8 ENSDARG00000057986 INTS8 Ints8 6 Not determined
ints9 ENSDARG00000067913 INTS9 Ints9 1 Not determined
invs ENSDARG00000002213 INVS Invs 5 Not determined
ip6k2 ENSDARG00000008310 IP6K2 Ip6k2 1 Not determined
ipo13 ENSDARG00000060618 IPO13 Ipo13 2 Not determined
ipo7 ENSDARG00000035751 IPO7 Ipo7 3 Not determined
ipo9 ENSDARG00000016753 IPO9 Ipo9 1 Not determined
ippk ENSDARG00000003446 IPPK Ippk 1 Not determined
iqca1 ENSDARG00000057276 IQCA1 4931409K22Rik 2 Not determined
iqgap2 ENSDARG00000060010 IQGAP2 Iqgap2 1 Not determined
IQSEC1 ENSDARG00000016551 IQSEC1 Iqsec1 3 Not determined
irak1 ENSDARG00000093174 None None 1 Not determined
irak3 ENSDARG00000053131 IRAK3 Irak3 1 Not determined
irbp ENSDARG00000059163 RBP3 Rbp3 2 Not determined
ireb2 ENSDARG00000021466 IREB2 Ireb2 5 Not determined
irf10 ENSDARG00000027658 None None 1 Not determined
IRF2 (1 of 2) ENSDARG00000040465 IRF2 Irf2 3 Not determined
irf2bp1 ENSDARG00000005468 IRF2BP1 Irf2bp1 3 Not determined
irf2bp2a ENSDARG00000004702 IRF2BP2 Irf2bp2 1 Not determined
irf2bp2b ENSDARG00000006275 IRF2BP2 Irf2bp2 1 Not determined
irf4a ENSDARG00000006560 IRF4 Irf4 1 Not determined
irf6 ENSDARG00000043296 IRF6 Irf6 2 Not determined
irf9 ENSDARG00000016457 IRF9 Irf9 3 Not determined
irge4 ENSDARG00000070317 None Tgtp1
Tgtp2
Igtp
Gm4841
AC132320.1
Iigp1
Irgc1
Ifi47
5 Normal
irgf1 ENSDARG00000070774 IRGM
IRGC
Irgc1
Ifi47
Tgtp1
Tgtp2
9930111J21Rik2
9930111J21Rik1
Irgm2
Igtp
Gm4841
Gm12185
AC132320.1
Gm5431
Iigp1
BC023105
Irgm1
Gm4951
3 Not determined
irgf2 ENSDARG00000092249 IRGM
IRGC
Irgc1
Ifi47
1 Not determined
IRS4 (1 of 2) ENSDARG00000052065 IRS4 Irs4 1 Not determined
irx1a ENSDARG00000009510 IRX1 Irx1 2 Not determined
irx1b ENSDARG00000056594 IRX3 Irx3 1 Not determined
irx2a ENSDARG00000001785 IRX2 Irx2 4 Not determined
irx3a ENSDARG00000052947 IRX3 Irx3 1 Not determined
irx3b ENSDARG00000031138 IRX3 Irx3 1 Not determined
irx4a ENSDARG00000035648 IRX4 Irx4 2 Not determined
irx4b ENSDARG00000036051 IRX4 Irx4 4 Normal
irx5a ENSDARG00000034043 IRX5 Irx5 2 Not determined
irx5b ENSDARG00000074070 IRX5 Irx5 1 Not determined
irx6a ENSDARG00000034420 IRX6 Irx6 3 Normal
irx7 ENSDARG00000002601 IRX1 Irx1 1 Not determined
isl2a ENSDARG00000003971 ISL2 Isl2 2 Not determined
islr2 ENSDARG00000051875 ISLR2
ISLR
Islr2
Islr
2 Not determined
ism1 ENSDARG00000020541 ISM1 Ism1 1 Not determined
ism2 ENSDARG00000053859 ISM2 Ism2 1 Not determined
ISM2 (1 of 2) ENSDARG00000089691 ISM2 Ism2 2 Not determined
isoc1 ENSDARG00000060069 ISOC1 Isoc1 2 Not determined
itch ENSDARG00000074903 ITCH Itch 1 Not determined
ITFG1 ENSDARG00000075584 ITFG1 Itfg1 4 Not determined
itga10 ENSDARG00000002507 ITGA10 Itga10 3 Not determined
itga11a ENSDARG00000036086 ITGA11 Itga11 5 Not determined
itga11b ENSDARG00000007950 ITGA11 Itga11 2 Not determined
itga2b ENSDARG00000018687 ITGA2B Itga2b 5 Normal
itga3a ENSDARG00000037917 ITGA7
ITGA6
Itga7
Itga6
2 Not determined
itga3b ENSDARG00000012824 ITGA7
ITGA6
Itga7
Itga6
1 Not determined
itga5 ENSDARG00000006353 ITGA5 Itga5 3 Not determined
itga6a ENSDARG00000042282 ITGA6 Itga6 3 Not determined
itga6b ENSDARG00000069946 ITGA6 Itga6 4 Not determined
ITGAE ENSDARG00000057787 ITGAE Itgae 4 Not determined
ITGAM ENSDARG00000002956 ITGAX
ITGAD
ITGAM
Itgad
Itgam
Itgax
4 Not determined
itgav ENSDARG00000006314 ITGAV Itgav 2 Not determined
itgb1a ENSDARG00000071863 ITGB1 Itgb1 3 Not determined
itgb1b.2 ENSDARG00000022689 ITGB1 Itgb1 1 Not determined
itgb1bp3 ENSDARG00000067848 ITGB1BP3 Itgb1bp3 1 Not determined
itgb3a ENSDARG00000056767 ITGB3 Itgb3 2 Not determined
itgb3b ENSDARG00000045070 ITGB3 Itgb3 2 Not determined
itgb4 ENSDARG00000028507 ITGB4 Itgb4 6 Not determined
itgb5 ENSDARG00000012942 ITGB5 Itgb5 2 Not determined
itih5 ENSDARG00000045517 ITIH5 Itih5 3 Not determined
itk ENSDARG00000017565 ITK Itk 1 Normal
itln3 ENSDARG00000003523 ITLN2
ITLN1
Itln1
Gm9765
1 Not determined
itln4 ENSDARG00000053630 ITLN2
ITLN1
Itln1
Gm9765
2 Normal
itm1 ENSDARG00000053832 STT3A Stt3a 4 Not determined
itm2ba ENSDARG00000007098 ITM2B Itm2b 1 Not determined
itm2bb ENSDARG00000041505 ITM2B Itm2b 1 Not determined
itm2ca ENSDARG00000043448 ITM2C Itm2c 1 Not determined
itm2cb ENSDARG00000039650 ITM2C Itm2c 1 Not determined
itpk1 ENSDARG00000013056 ITPK1 Itpk1 2 Not determined
itpka ENSDARG00000042856 ITPKA Itpka 3 Not determined
itpkc ENSDARG00000002994 ITPKC Itpkc 1 Not determined
ITPR1 (2 of 2) ENSDARG00000014655 ITPR1 Itpr1 9 Normal
itpr2 ENSDARG00000011909 ITPR2 Itpr2 6 Normal
itpr3 ENSDARG00000061741 ITPR3 Itpr3 10 Not determined
itsn1 ENSDARG00000000086 ITSN1 Itsn1 1 Not determined
ivd ENSDARG00000042853 IVD Ivd 2 Not determined
ivns1abpb ENSDARG00000013946 IVNS1ABP Ivns1abp 2 Not determined
IWS1 ENSDARG00000087950 IWS1 Iws1 1 Not determined
* quick link - http://q.sanger.ac.uk/r3o1j76l