Dr Manj Sandhu

Manj's research explores genomic diversity and its impact on infectious and cardiometabolic risk factors among populations.

Manj studied physiology at King's College, London University. He then completed masters and doctoral training in epidemiology and public health and molecular epidemiology at the London School of Hygiene and Tropical Medicine and the Department of Public Health and Primary Care (PHPC), University of Cambridge, respectively.

Following his PhD studies, Manj was awarded an MRC Fellowship in cardiovascular genetic epidemiology and in 2004 was appointed University Lecturer in Epidemiology at PHPC, University of Cambridge. He is actively involved in research training. His is a former Course Director for the MPhil in Epidemiology Degree, taking academic and strategic responsibility for research training in epidemiology and statistics. As part of his current academic post, he lectures on the MPhils in Epidemiology and in Public Health. He is also a member of the Degree Committee of the Faculty of Clinical Medicine, which oversees the Faculty's masters and doctoral programmes. As part of a joint appointment with the University of Cambridge, Manj joined the Wellcome Trust Sanger Institute Faculty as a Group Leader in 2009.

Manj's research focuses on the integration of principles and procedures underlying population genetics and epidemiology. Together with current and emerging genome-wide technologies, this approach provides unparalleled opportunities to identify the biological mechanisms underlying the development of complex diseases and traits. His work has largely centred on the genetic basis of cardiometabolic traits and diseases, particularly lipid metabolism and coronary artery disease, and the use of genetic tools for causal inference. More recently, he has begun developing epidemiological resources to explore genomic diversity and its impact on infectious and cardiometabolic risk factors and diseases in Sub-Saharan African populations, as part of a public health and epidemiological research programme.

Selected Publications

  • Common variants in WFS1 confer risk of type 2 diabetes.

    Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, Daly A, Lango H, Frayling TM, Neumann RJ, Sherva R, Blech I, Pharoah PD, Palmer CN, Kimber C, Tavendale R, Morris AD, McCarthy MI, Walker M, Hitman G, Glaser B, Permutt MA, Hattersley AT, Wareham NJ and Barroso I

    Nature genetics 2007;39;8;951-3

[Genome Research Limited]

Manj's Project
Genetic Epidemiology
Research Area
Human Genetics
* quick link - http://q.sanger.ac.uk/fp1x9g6f