Associate Faculty - Eric Miska

Eric Miska is the Herchel Smith Professor of Molecular Genetics at the University of Cambridge and a Senior Group Leader at the Gurdon Institute studying the roles of non-coding RNA in gene regulation, epigenetic control, transgenerational inheritance and genome evolution. Eric has been collaborating with several teams at the Sanger Institute since 2005. For example, together with Allan Bradley's group he investigates the function of miRNA genes using mouse genetics. Together with Richard Durbin, Eric is studying the genomics of cichlid radiation in the great lakes of East Africa.

Eric studied mathematics, physics and biology at Heidelberg, Berlin and Mainz and received a BA in Biochemistry from Trinity College, Dublin, in 1996. He received his PhD in pathology from the University of Cambridge, UK, in 2000, working with Tony Kouzarides. He was a postdoctoral fellow in the laboratory of nobel laureate (2002) Bob Horvitz at the Massachusetts Institute of Technology, Cambridge, Massachusetts, USA from 2000 to 2004. He started his own research group at the Gurdon Institute in 2005.

Now Eric is the Herchel Smith Professor of Molecular Genetics and a Senior Group Leader at the Gurdon Institute at the University of Cambridge. Eric has an appointment as associated faculty at the Cambridge Systems Biology Centre and the Cancer Research UK Cambridge Research Institute. Eric was an EMBO Young Investigator and is a full member of EMBO since 2012. Eric is the 2013 recipient of the Hooke Medal awarded by the British Society of Cell Biology.

Selected Publications

  • Molecular biology. Is there social RNA?

    Sarkies P and Miska EA

    Science (New York, N.Y.) 2013;341;6145;467-8

  • A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity.

    Ashe A, Bélicard T, Le Pen J, Sarkies P, Frézal L, Lehrbach NJ, Félix MA and Miska EA

    eLife 2013;2;e00994

  • Function, targets, and evolution of Caenorhabditis elegans piRNAs.

    Bagijn MP, Goldstein LD, Sapetschnig A, Weick EM, Bouasker S, Lehrbach NJ, Simard MJ and Miska EA

    Science (New York, N.Y.) 2012;337;6094;574-8

  • piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans.

    Ashe A, Sapetschnig A, Weick EM, Mitchell J, Bagijn MP, Cording AC, Doebley AL, Goldstein LD, Lehrbach NJ, Le Pen J, Pintacuda G, Sakaguchi A, Sarkies P, Ahmed S and Miska EA

    Cell 2012;150;1;88-99

  • Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline.

    Das PP, Bagijn MP, Goldstein LD, Woolford JR, Lehrbach NJ, Sapetschnig A, Buhecha HR, Gilchrist MJ, Howe KL, Stark R, Matthews N, Berezikov E, Ketting RF, Tavaré S and Miska EA

    Molecular cell 2008;31;1;79-90

  • MicroRNA expression profiles classify human cancers.

    Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR and Golub TR

    Nature 2005;435;7043;834-8

[Gurdon Institute]

Molecular Genetics
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