Alexander Strong | Advanced Research Assistant

Strong, Alexander

Alex manages a number of transposon-based insertional mutagenesis screens in mice. Using mouse lines developed within the Bradley lab he conducts constitutive, tissue-specific, dominant and recessive genetic screens. He also works to validate and further study the genes highlighted by these screens.

Publications

  • CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.

    Weber J, Öllinger R, Friedrich M, Ehmer U, Barenboim M et al.

    Proceedings of the National Academy of Sciences of the United States of America 2015;112;45;13982-7

  • A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.

    Dietlein F, Kalb B, Jokic M, Noll EM, Strong A et al.

    Cell 2015;162;1;146-59

  • A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.

    Rad R, Rad L, Wang W, Strong A, Ponstingl H et al.

    Nature genetics 2015;47;1;47-56

  • A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.

    Rad R, Cadiñanos J, Rad L, Varela I, Strong A et al.

    Cancer cell 2013;24;1;15-29

  • PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

    Rad R, Rad L, Wang W, Cadinanos J, Vassiliou G et al.

    Science (New York, N.Y.) 2010;330;6007;1104-7

Strong, Alexander
Alexander's Timeline
2009

Advanced Research Assistant at Wellcome Trust Sanger Institute in the Bradley Faculty

2004

Scientist at GlaxoSmithKline working in drug metabolism and pharmacokinetics