Dr Andrew Knights | Senior Staff Scientist

Knights, Andrew

Andrew currently uses functional genomics assays such as ATAC-seq, RNA-seq and ChIP-seq to provide sequencing data for the computational side of the Gaffney Faculty. The main focus is to map causal variants within human populations. Andrew is also using Cas9/CRISPR technology to validate putative causal SNPs.

Publications

  • Fine-mapping cellular QTLs with RASQUAL and ATAC-seq.

    Kumasaka N, Knights AJ and Gaffney DJ

    Nature genetics 2016;48;2;206-13

  • Oct-2 forms a complex with Oct-1 on the iNOS promoter and represses transcription by interfering with recruitment of RNA PolII by Oct-1.

    Bentrari F, Chantôme A, Knights A, Jeannin JF and Pance A

    Nucleic acids research 2015;43;20;9757-65

  • Extent, causes, and consequences of small RNA expression variation in human adipose tissue.

    Parts L, Hedman ÅK, Keildson S, Knights AJ, Abreu-Goodger C et al.

    PLoS genetics 2012;8;5;e1002704

  • Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling.

    Cohen M, Reale V, Olofsson B, Knights A, Evans P and de Bono M

    Cell metabolism 2009;9;4;375-85

Knights, Andrew
Andrew's Timeline
2012

Joined the Gaffney Faculty, Wellcome Trust Sanger Institute

2010

Staff Scientist, Illumina Library Team, Wellcome Trust Sanger Institute

2008

Post Doc, Cell Signalling, Babraham Institute, Cambridge

2004

PhD, Cell Signalling, Babraham Institute, Cambridge

1999

Human Genome Project, Team 53, Wellcome Trust Sanger Institute

1995

BSc Hons Biochemistry and Microbiology, University of Sheffield