Mareike Herzog | PhD Student

This person is a member of Sanger Institute Alumni.

Herzog, Mareike

As a shared PhD student between David Adams (Experimental Cancer Genetics) and Steve Jackson (DNA repair), Mareike is looking at how mutations in DNA polymerases - the molecular machines that copy and duplicate DNA - contribute to tumorigenesis. The aim is to understand which mutations promote cancers, to what extent and why. This work uses classical genetics as well as next generation sequencing technologies to examine these mutations in model systems such as S. cerevisiae and cultured human cells. Beyond that, she contributes to a variety of projects on DNA repair genetics and genome stability by analysing next generation sequencing data and providing other bioinformatical analysis.


  • Synthetic viability genomic screening defines Sae2 function in DNA repair.

    Puddu F, Oelschlaegel T, Guerini I, Geisler NJ, Niu H et al.

    The EMBO journal 2015;34;11;1509-22

  • Global reorganization of budding yeast chromosome conformation in different physiological conditions.

    Dultz E, Tjong H, Weider E, Herzog M, Young B et al.

    The Journal of cell biology 2016;212;3;321-34

  • IP3 signalling regulates exogenous RNAi in Caenorhabditis elegans.

    Nagy AI, Vázquez-Manrique RP, Lopez M, Christov CP, Sequedo MD et al.

    EMBO reports 2015;16;3;341-50

Herzog, Mareike
Mareike's Timeline

Start of PhD at Wellcome Trust Sanger Institute, UK

BA in Natural Sciences, University of Cambridge, UK


Visiting student with Karsten Weis, University of California Berkeley


Abitur, Deutsche Internationale Schule Den Haag, Netherlands