Claire Hardy | Senior Research Assistant

Hardy, Claire

Claire works alongside Calli Latimer and Laura Mudie to coordinate the reception, QC and sequencing of samples within the Cancer Faculty; facilitating efficient progression of associated projects through laboratory pipelines.

Publications

  • Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.

    Cooper CS, Eeles R, Wedge DC, Van Loo P, Gundem G et al.

    Nature genetics 2015;47;6;689

  • Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.

    Cooper CS, Eeles R, Wedge DC, Van Loo P, Gundem G et al.

    Nature genetics 2015;47;4;367-372

  • Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

    Tubio JMC, Li Y, Ju YS, Martincorena I, Cooke SL et al.

    Science (New York, N.Y.) 2014;345;6196;1251343

  • Recurrent PTPRB and PLCG1 mutations in angiosarcoma.

    Behjati S, Tarpey PS, Sheldon H, Martincorena I, Van Loo P et al.

    Nature genetics 2014;46;4;376-379

  • Clinical and biological implications of driver mutations in myelodysplastic syndromes.

    Papaemmanuil E, Gerstung M, Malcovati L, Tauro S, Gundem G et al.

    Blood 2013;122;22;3616-27; quiz 3699

  • Whole exome sequencing of adenoid cystic carcinoma.

    Stephens PJ, Davies HR, Mitani Y, Van Loo P, Shlien A et al.

    The Journal of clinical investigation 2013;123;7;2965-8

  • Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.

    Tarpey PS, Behjati S, Cooke SL, Van Loo P, Wedge DC et al.

    Nature genetics 2013;45;8;923-6

  • Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

    Varela I, Tarpey P, Raine K, Huang D, Ong CK et al.

    Nature 2011;469;7331;539-42

  • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.

    Dalgliesh GL, Furge K, Greenman C, Chen L, Bignell G et al.

    Nature 2010;463;7279;360-3

  • A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.

    Tarpey PS, Smith R, Pleasance E, Whibley A, Edkins S et al.

    Nature genetics 2009;41;5;535-43

  • Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.

    van Haaften G, Dalgliesh GL, Davies H, Chen L, Bignell G et al.

    Nature genetics 2009;41;5;521-3

  • X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment.

    Dibbens LM, Tarpey PS, Hynes K, Bayly MA, Scheffer IE et al.

    Nature genetics 2008;40;6;776-81

  • Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing.

    Campbell PJ, Stephens PJ, Pleasance ED, O'Meara S, Li H et al.

    Nature genetics 2008;40;6;722-9

  • Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation.

    Tarpey PS, Raymond FL, Nguyen LS, Rodriguez J, Hackett A et al.

    Nature genetics 2007;39;9;1127-33

  • Patterns of somatic mutation in human cancer genomes.

    Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C et al.

    Nature 2007;446;7132;153-8

  • Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.

    Tarpey PS, Stevens C, Teague J, Edkins S, O'Meara S et al.

    American journal of human genetics 2006;79;6;1119-24

  • Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

    Ikediobi ON, Davies H, Bignell G, Edkins S, Stevens C et al.

    Molecular cancer therapeutics 2006;5;11;2606-12

  • Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus.

    Tarpey P, Thomas S, Sarvananthan N, Mallya U, Lisgo S et al.

    Nature genetics 2006;38;11;1242-4

  • Recurrent KRAS codon 146 mutations in human colorectal cancer.

    Edkins S, O'Meara S, Parker A, Stevens C, Reis M et al.

    Cancer biology & therapy 2006;5;8;928-32

  • A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.

    Hunter C, Smith R, Cahill DP, Stephens P, Stevens C et al.

    Cancer research 2006;66;8;3987-91

  • High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison.

    Davies H, Dicks E, Stephens P, Cox C, Teague J et al.

    Genomics 2006;87;3;427-32

  • Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.

    Bignell G, Smith R, Hunter C, Stephens P, Davies H et al.

    Genes, chromosomes & cancer 2006;45;1;42-6

  • Somatic mutations of the protein kinase gene family in human lung cancer.

    Davies H, Hunter C, Smith R, Stephens P, Greenman C et al.

    Cancer research 2005;65;17;7591-5

  • A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.

    Stephens P, Edkins S, Davies H, Greenman C, Cox C et al.

    Nature genetics 2005;37;6;590-2

  • Lung cancer: intragenic ERBB2 kinase mutations in tumours.

    Stephens P, Hunter C, Bignell G, Edkins S, Davies H et al.

    Nature 2004;431;7008;525-6

  • Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation.

    Tarpey P, Parnau J, Blow M, Woffendin H, Bignell G et al.

    American journal of human genetics 2004;75;2;318-24

  • Mutations of the BRAF gene in human cancer.

    Davies H, Bignell GR, Cox C, Stephens P, Edkins S et al.

    Nature 2002;417;6892;949-54