Dr Giuseppe Gallone | Senior Computer Biologist

Gallone, Dr

Giuseppe is the senior computational biologist for the Deciphering Developmental Disorders (DDD) study.

His role in the team is to process, analyse and summarise the DDD raw data, to maintain and design the DDD data processing pipelines and to assist the team with the processing and interpretation of the clinically relevant DNA variants evidenced by the analysis pipelines.

Publications

  • Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease.

    Gallone G, Haerty W, Disanto G, Ramagopalan SV, Ponting CP and Berlanga-Taylor AJ

    Human molecular genetics 2017;26;11;2164-2176

  • Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain.

    Handel AE, Gallone G, Zameel Cader M and Ponting CP

    Human molecular genetics 2017;26;1;79-89

  • Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells.

    Žuklys S, Handel A, Zhanybekova S, Govani F, Keller M et al.

    Nature immunology 2016;17;10;1206-1215

  • Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease.

    Gallone G, Haerty W, Disanto G, Ramagopalan SV, Ponting CP and Berlanga-Taylor AJ

    Human molecular genetics 2017;26;11;2164-2176

  • Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain.

    Handel AE, Gallone G, Zameel Cader M and Ponting CP

    Human molecular genetics 2017;26;1;79-89

  • Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells.

    Žuklys S, Handel A, Zhanybekova S, Govani F, Keller M et al.

    Nature immunology 2016;17;10;1206-1215

  • Mutations in ZMYND10, a gene essential for proper axonemal assembly of inner and outer dynein arms in humans and flies, cause primary ciliary dyskinesia.

    Moore DJ, Onoufriadis A, Shoemark A, Simpson MA, zur Lage PI et al.

    American journal of human genetics 2013;93;2;346-56

  • Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease.

    Handel AE, Sandve GK, Disanto G, Berlanga-Taylor AJ, Gallone G et al.

    BMC medicine 2013;11;163

  • Bio::Homology::InterologWalk--a Perl module to build putative protein-protein interaction networks through interolog mapping.

    Gallone G, Simpson TI, Armstrong JD and Jarman AP

    BMC bioinformatics 2011;12;289

Gallone, Dr