Dr Oliver M Dovey | Postdoctoral Fellow

Dovey, Oliver M

Oliver's research is focused on resolving the cellular and molecular defects in Acute Myeloid Leukaemia (AML), using both forward and reverse genetic approaches.Through cateloguing the characteristics of leukaemic cells he aims to identify and validate potential novel therapeutic strategies in the treatment of AML.

Publications

  • Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.

    Dovey OM, Foster CT, Conte N, Edwards SA, Edwards JM et al.

    Blood 2013;121;8;1335-44

  • Emphasizing the positive: A role for histone deacetylases in transcriptional activation.

    Dovey OM, Foster CT and Cowley SM

    Cell cycle (Georgetown, Tex.) 2010;9;14;2700-1

  • A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice.

    Mupo A, Celani L, Dovey O, Cooper JL, Grove C et al.

    Leukemia 2013;27;9;1917-20

  • Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation.

    Dovey OM, Foster CT and Cowley SM

    Proceedings of the National Academy of Sciences of the United States of America 2010;107;18;8242-7

  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

    ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R et al.

    Nature 2007;447;7146;799-816

  • Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells.

    Jamaladdin S, Kelly RD, O'Regan L, Dovey OM, Hodson GE et al.

    Proceedings of the National Academy of Sciences of the United States of America 2014;111;27;9840-5

  • A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice.

    Mupo A, Celani L, Dovey O, Cooper JL, Grove C et al.

    Leukemia 2013;27;9;1917-20

  • Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.

    Dovey OM, Foster CT, Conte N, Edwards SA, Edwards JM et al.

    Blood 2013;121;8;1335-44

  • Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability.

    Foster CT, Dovey OM, Lezina L, Luo JL, Gant TW et al.

    Molecular and cellular biology 2010;30;20;4851-63

  • Emphasizing the positive: A role for histone deacetylases in transcriptional activation.

    Dovey OM, Foster CT and Cowley SM

    Cell cycle (Georgetown, Tex.) 2010;9;14;2700-1

  • Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation.

    Dovey OM, Foster CT and Cowley SM

    Proceedings of the National Academy of Sciences of the United States of America 2010;107;18;8242-7

  • Loss of Rassf1a cooperates with Apc(Min) to accelerate intestinal tumourigenesis.

    van der Weyden L, Arends MJ, Dovey OM, Harrison HL, Lefebvre G et al.

    Oncogene 2008;27;32;4503-8

  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

    ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R et al.

    Nature 2007;447;7146;799-816

  • The landscape of histone modifications across 1% of the human genome in five human cell lines.

    Koch CM, Andrews RM, Flicek P, Dillon SC, Karaöz U et al.

    Genome research 2007;17;6;691-707

  • Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes.

    Rada-Iglesias A, Enroth S, Ameur A, Koch CM, Clelland GK et al.

    Genome research 2007;17;6;708-19

  • Accurate and reliable high-throughput detection of copy number variation in the human genome.

    Fiegler H, Redon R, Andrews D, Scott C, Andrews R et al.

    Genome research 2006;16;12;1566-74

  • Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse.

    Natrajan R, Williams RD, Hing SN, Mackay A, Reis-Filho JS et al.

    The Journal of pathology 2006;210;1;49-58

  • The DNA sequence and biological annotation of human chromosome 1.

    Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D et al.

    Nature 2006;441;7091;315-21

Dovey, Oliver M
Oliver's Timeline
2011

Joined Haematoligical Cancer Genetics Group, Sanger Institute as a Post Doctoral Fellow.

Awarded PhD from the University of Leicester

2007

Joined the Cowley Lab, Department of Biochemistry, University of Leicester.

2005

Research Assistant, Bradley Lab, Sanger Institute.

2002

Research Assistant, Microarray Facility, Sanger Institute.