Dr Lorenzo Bomba | Postdoctoral Fellow

Bomba, Lorenzo

I am a postdoctoral fellow with a wide range of experience in molecular biology and genomic data analysis. I was trained in quantitative genetics in animal breeding, and recently switched to human genetics. My objective now is study genetic predisposition to complex disease using large-scale metabolomics studies (mGWAS), with the final aim to developed safe and effective therapies.

I graduated from Perugia University (Italy) with a master degree in science and technology of animal production in 2007. I won a Socrates program scholarship at SLU University, in Uppsala, Sweden, working on microsatellite analysis in 2006. I later moved to the Institute of Zootechnics, Faculty of Agriculture, Università Cattolica del S. Cuore (Piacenza, Italy). From 2009 to 2011, I completed the Agrisystem doctoral school program, receiving the Ph.D. degree in Animal Science in 2012. During this period I spent six months at the Wellcome Trust Sanger Institute to train in SNP array and sequence data analysis and genome-wide association studies. I was involved in several national and European projects aiming to study various aspects of animal biology using genomic data analysis in livestock species. In 2014-2015 I spent 8 months at the AgriBio Research Institute, located in Melbourne, Australia working on WGS data searching for signature of selection in African Cattle.

Publications

  • Relative extended haplotype homozygosity signals across breeds reveal dairy and beef specific signatures of selection.

    Bomba L, Nicolazzi EL, Milanesi M, Negrini R, Mancini G et al.

    Genetics, selection, evolution : GSE 2015;47;25

  • New gene functions in megakaryopoiesis and platelet formation.

    Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E et al.

    Nature 2011;480;7376;201-8

  • Small effective population size and genetic homogeneity in the Val Borbera isolate.

    Colonna V, Pistis G, Bomba L, Mona S, Matullo G et al.

    European journal of human genetics : EJHG 2013;21;1;89-94

  • Searching new signals for production traits through gene-based association analysis in three Italian cattle breeds.

    Capomaccio S, Milanesi M, Bomba L, Cappelli K, Nicolazzi EL et al.

    Animal genetics 2015;46;4;361-70

  • Relative extended haplotype homozygosity signals across breeds reveal dairy and beef specific signatures of selection.

    Bomba L, Nicolazzi EL, Milanesi M, Negrini R, Mancini G et al.

    Genetics, selection, evolution : GSE 2015;47;25

  • Gut response induced by weaning in piglet features marked changes in immune and inflammatory response.

    Bomba L, Minuti A, Moisá SJ, Trevisi E, Eufemi E et al.

    Functional & integrative genomics 2014;14;4;657-71

  • The nutrigenomic investigation of C57BL/6N mice fed a short-term high-fat diet highlights early changes in clock genes expression.

    Lizier M, Bomba L, Minuti A, Chegdani F, Capraro J et al.

    Genes & nutrition 2013;8;5;465-74

  • Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci.

    Paul DS, Albers CA, Rendon A, Voss K, Stephens J et al.

    Genome research 2013;23;7;1130-41

  • Small effective population size and genetic homogeneity in the Val Borbera isolate.

    Colonna V, Pistis G, Bomba L, Mona S, Matullo G et al.

    European journal of human genetics : EJHG 2013;21;1;89-94

  • A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.

    Nürnberg ST, Rendon A, Smethurst PA, Paul DS, Voss K et al.

    Blood 2012;120;24;4859-68

  • New gene functions in megakaryopoiesis and platelet formation.

    Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E et al.

    Nature 2011;480;7376;201-8

Bomba, Lorenzo
Lorenzo's Timeline
2015

Visiting Scientist at AgriBio,Department of computational biology, Bundoora, VIC, Australia

2013

Visiting Scientist at São Paulo State University, UNESP, Brazil

2012

Post doctoral Fellow, istituto di Zootecnica, Università Cattolica del Sacro Cuore, Piacenza, Italy

Ph.D. in Animal Science (Agrisystem Ph.D. School), istituto di Zootecnica, Università Cattolica del Sacro Cuore, Piacenza, Italy

2010

Visiting Ph.D student at Sanger Institute, Department of Human genetics, Cambridge, UK

2007

Master degree in Animal Production, cum laude

Erasmus student at Swedish University of Agricultural Sciences, Uppsala, Sweden