Banerjee, Ruby
Currently I work in the Molecular Cytogenetics Core Facility popularly known as the 'FISH group' in the Institute. After obtaining my PhD titled 'Synaptonemal Complex studies in Higher Plants' (School of Biological Sciences, University of Birmingham, 1996) I joined the Mammalian Genetics Unit, Medical research Council, Harwell, Oxfordshire the same year. Here, I specialised in mouse cytogenetics till 2001(Oct).
Since 2001 (Nov.) I had been based at the Sanger Institute and my molecular cytogenetic work encompasses human, mouse, zebrafish and other species as outlined in some of my selected publications.
Publications
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G&T-seq: parallel sequencing of single-cell genomes and transcriptomes.
Nature methods 2015;12;6;519-22
PUBMED: 25915121; DOI: 10.1038/nmeth.3370
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A global reference for human genetic variation.
Nature 2015;526;7571;68-74
PUBMED: 26432245; PMC: 4750478; DOI: 10.1038/nature15393
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A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
Nature medicine 2014;20;11;1340-1347
PUBMED: 25326799; PMC: 4270133; DOI: 10.1038/nm.3646
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Fine mapping of the pond snail left-right asymmetry (chirality) locus using RAD-Seq and fibre-FISH.
PloS one 2013;8;8;e71067
PUBMED: 23951082; PMC: 3741322; DOI: 10.1371/journal.pone.0071067
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The zebrafish reference genome sequence and its relationship to the human genome.
Nature 2013;496;7446;498-503
PUBMED: 23594743; PMC: 3703927; DOI: 10.1038/nature12111
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Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome.
PloS one 2013;8;4;e60482
PUBMED: 23596509; PMC: 3626651; DOI: 10.1371/journal.pone.0060482
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PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.
Science (New York, N.Y.) 2010;330;6007;1104-7
PUBMED: 20947725; PMC: 3719098; DOI: 10.1126/science.1193004
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Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice.
Nature genetics 2011;43;5;470-5
PUBMED: 21441929; PMC: 3084174; DOI: 10.1038/ng.796
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Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling.
Genes & development 2010;24;13;1377-88
PUBMED: 20551164; PMC: 2895197; DOI: 10.1101/gad.580710