News Archive

News Archive

Sir John Sulston awarded the 2002 Nobel Prize for Physiology or Medicine

Sir John Sulston awarded the 2002 Nobel Prize for Physiology or Medicine

In 1992, Sulston was appointed the first Director of the Wellcome Trust Sanger Institute in Cambridgeshire which made the UK's contribution to the international Human Genome Project.

Following publication of the first draft sequence of the human genome in 2000 he was listed among the UK's 100 most powerful people by the Observer newspaper. Sir John received his knighthood for services to genome research in the 2001 New Year's Honours. He stepped down as Director in September 2000 but continues to work on C. elegans at the Institute.

Double Success In Fight Against Malaria

Double Success In Fight Against Malaria

A major breakthrough in the fight against malaria is announced today (3 October 2002) by an international collaboration of scientists in the UK and America.

A six-year project to sequence the genome of the Plasmodium falciparum parasite, which causes the most deadly form of malaria and kills one child every 20 seconds, has been completed.

Maps Of Mice - And Men

Maps Of Mice - And Men

International consortium maps 98% of the mouse genome

The map has already proven a valuable resource in the hunt for mouse and - even more importantly - human genes.

Scientists Identify Gene Involved In 70 Percent Of Melanomas

Scientists Identify Gene Involved In 70 Percent Of Melanomas

Researchers have identified a major genetic change that leads to malignant melanoma, a potentially lethal form of skin cancer that kills more than 1600 people per year in the UK.

Researchers say that the mutation, which makes skin cells grow out of control, is so clear-cut that drugs are already being designed to block the action of the defective gene.

Wellcome Trust Sanger Institute's Director Honoured: Allan Bradley Elected to Royal Society

Wellcome Trust Sanger Institute's Director Honoured: Allan Bradley Elected to Royal Society

Professor Allan Bradley, Director of the Wellcome Trust Sanger Institute, has been elected to Fellowship of the Royal Society, an honour regarded as the UK's premier scientific accolade.

Professor Bradley took over as Director of the Wellcome Trust Sanger Institute in 2000 to develop programmes to capitalize on decoding the human genome and other genomes. He is a world leader in the field of stem cell research - methods he and his colleagues developed in the early 1980s that today provide one of the most promising routes for understanding and treating genetic disease

Scientists sequence Nature's antibiotic factory

Scientists sequence Nature's antibiotic factory

The genome sequence of Streptomyces coelicolor, one of the family of common soil bacteria that produce more than two thirds of the world's antibiotic medicines, is published in the journal Nature.

Streptomyces are almost ubiquitous in the soils and are responsible for its familiar 'earthy' smell. The genome data, collected by British scientists from the John Innes Centre and The Wellcome Trust Sanger Institute, is already being used in research that will help develop new types of antibiotics, anticancer agents and other beneficial chemicals.

International Team of Researchers Assembles Draft Sequence of Mouse Genome

International Team of Researchers Assembles Draft Sequence of Mouse Genome

Ninety-six percent of mouse genome sequenced; Results freely available in public databases on Internet

This achievement represents a major milestone for the Human Genome Project because it provides a key tool needed to interpret the human sequence, a draft version of which was published last year. Researchers will be better able to understand the function of many human genes because the mouse carries virtually the same set of genes as the human but can be used in laboratory research.

Wellcome Trust Proposal To Extend Genome Campus

Wellcome Trust Proposal To Extend Genome Campus

The proposal will extend the leading genome centre to include a post-genomic research facility for academic and industry scientists.

The proposed extension will provide cutting-edge academic research facilities for the Sanger Institute as it progresses from sequencing the human genome to discovering what genes do. It will also include an Innovation Centre for genomics start-up companies and space for grow-on companies seeking to expand.

MHC Haplotype Consortium Web Resource

MHC Haplotype Consortium Web Resource

A Cambridge-based Consortium today announced a new web resource designed to help medical researchers in the fight against diseases like diabetes, rheumatoid arthritis and multiple sclerosis.

The MHC Haplotype Consortium - formed by researchers at the Wellcome Trust Sanger Institute and the University of Cambridge - will define the most common differences in DNA code that can lead to these diseases. An accurate molecular understanding should lead to improved diagnosis and treatment.

The complete genome of Mycobacterium bovis has been sequenced

The complete genome of Mycobacterium bovis has been sequenced

A step forward in the fight against bovine tuberculosis: The complete genome of Mycobacterium bovis has been sequenced

The sequencing project has revealed that the genome of M. bovis is greater than 99.9% identical to Mycobacterium tuberculosis, the causative agent of human tuberculosis, which kills over two million people a year. Analysis of the two genomes has revealed an unexpected evolutionary scenario for the development of these two pathogens. Since the M. bovis genome is smaller than that of M. tuberculosis, it is more likely that man gave tuberculosis to cattle or that the two organisms evolved separately from a common ancestor.

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