5 Dec 2002

Mouse genome dictionary identifies 1200 new genes in the human book of life. The sequence and analysis of more than 95 percent of the mouse genome is published for the first time in today's edition of Nature (5 December).

In addition to revealing 9000 new mouse genes, the research papers reveal 1200 new human genes, a significant number of which are likely to be involved in cancers and other diseases. These findings will allow researchers to home in more rapidly on genes in order to better diagnose and treat many human diseases.

7 Nov 2002

Planning permission has been granted for a 27,000 sqm extension to the Wellcome Trust Genome Campus at Hinxton, home to the internationally renowned Sanger Institute.

The new development will bring industry and academic scientists together to allow data emerging from the Sanger Institute's flagship venture, the Human Genome Project, to be translated into practical health benefits.

7 Oct 2002

In 1992, Sulston was appointed the first Director of the Wellcome Trust Sanger Institute in Cambridgeshire which made the UK's contribution to the international Human Genome Project.

Following publication of the first draft sequence of the human genome in 2000 he was listed among the UK's 100 most powerful people by the Observer newspaper. Sir John received his knighthood for services to genome research in the 2001 New Year's Honours. He stepped down as Director in September 2000 but continues to work on C. elegans at the Institute.

3 Oct 2002

A major breakthrough in the fight against malaria is announced today (3 October 2002) by an international collaboration of scientists in the UK and America.

A six-year project to sequence the genome of the Plasmodium falciparum parasite, which causes the most deadly form of malaria and kills one child every 20 seconds, has been completed.

5 Aug 2002

International consortium maps 98% of the mouse genome

The map has already proven a valuable resource in the hunt for mouse and - even more importantly - human genes.

9 Jun 2002

Researchers have identified a major genetic change that leads to malignant melanoma, a potentially lethal form of skin cancer that kills more than 1600 people per year in the UK.

Researchers say that the mutation, which makes skin cells grow out of control, is so clear-cut that drugs are already being designed to block the action of the defective gene.

13 May 2002

Professor Allan Bradley, Director of the Wellcome Trust Sanger Institute, has been elected to Fellowship of the Royal Society, an honour regarded as the UK's premier scientific accolade.

Professor Bradley took over as Director of the Wellcome Trust Sanger Institute in 2000 to develop programmes to capitalize on decoding the human genome and other genomes. He is a world leader in the field of stem cell research - methods he and his colleagues developed in the early 1980s that today provide one of the most promising routes for understanding and treating genetic disease

9 May 2002

The genome sequence of Streptomyces coelicolor, one of the family of common soil bacteria that produce more than two thirds of the world's antibiotic medicines, is published in the journal Nature.

Streptomyces are almost ubiquitous in the soils and are responsible for its familiar 'earthy' smell. The genome data, collected by British scientists from the John Innes Centre and The Wellcome Trust Sanger Institute, is already being used in research that will help develop new types of antibiotics, anticancer agents and other beneficial chemicals.

6 May 2002

Ninety-six percent of mouse genome sequenced; Results freely available in public databases on Internet

This achievement represents a major milestone for the Human Genome Project because it provides a key tool needed to interpret the human sequence, a draft version of which was published last year. Researchers will be better able to understand the function of many human genes because the mouse carries virtually the same set of genes as the human but can be used in laboratory research.

16 Apr 2002

The proposal will extend the leading genome centre to include a post-genomic research facility for academic and industry scientists.

The proposed extension will provide cutting-edge academic research facilities for the Sanger Institute as it progresses from sequencing the human genome to discovering what genes do. It will also include an Innovation Centre for genomics start-up companies and space for grow-on companies seeking to expand.