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Mammalian Phenotype
Chromosome
Marker Symbol

Browsing Data by Marker Symbol: 'U'

Ube2uos

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube2uos was found for the following reasons:
marker_name - ubiquitin-conjugating enzyme E2U (putative), opposite strand
symbol - Ube2uos
marker_symbol_str - Ube2uos
marker_symbol - Ube2uos
marker_type - unclassified gene

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

Ube2v1

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube2v1 was found for the following reasons:
marker_name - ubiquitin-conjugating enzyme E2 variant 1
symbol - Ube2v1
interpro_desc - UBQ-conjugating_enzyme/RWD
marker_symbol_str - Ube2v1
marker_symbol - Ube2v1
interpro - IPR000608||UBQ-conjugat_E2||Ubiquitin-conjugating enzyme, E2

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
32 2 0 0 view in Ensembl

Ube2v2

Ube2v2 was found for the following reasons:
marker_name - ubiquitin-conjugating enzyme E2 variant 2
symbol - Ube2v2
interpro_desc - UBQ-conjugating_enzyme/RWD
marker_symbol_str - Ube2v2
marker_symbol - Ube2v2
interpro - IPR000608||UBQ-conjugat_E2||Ubiquitin-conjugating enzyme, E2

Gene Details

Marker Name(s): ubiquitin-conjugating enzyme E2 variant 2
view this gene in MGI
Marker Type: protein coding gene
Synonyms: 1110021H13Rik, 4632410D19Rik, 5730524P06Rik, AI848315, C81524, MMS2
Location: Chr16:15552677-15594524(-)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:1917870 Ensembl Gene ID: ENSMUSG00000022674 Vega Gene ID: OTTMUSG00000025687
Entrez Gene ID: 70620 CCDS ID:
Interpro Families
Orthologs / Homologs
Species Marker Symbol Entrez Gene ID Ensembl Gene ID
Human UBE2V2 7336
Rat Ube2v2 287927

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
(Project: 81271)
order order view details

ES Cell Clones

Cassette Type 2 Knockout-First Alleles 0 Targeted Non-Conditional Alleles
Promotor Driven
Allele: genbank file | image
Targeting Vector: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
HEPD0733_4_C08 PG00236_Z_8_B05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(EUCOMM)Hmgu Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA fail LOXP fail LACZ pass
Chromosome 1 pass Chromosome 8a pass Chromosome 8b -
Chromosome 11a - Chromosome 11b pass Chromosome Y fail
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
HEPD0733_4_G06 PG00236_Z_8_B05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(EUCOMM)Hmgu Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA pass LOXP pass LACZ pass
Chromosome 1 pass Chromosome 8a pass Chromosome 8b -
Chromosome 11a - Chromosome 11b pass Chromosome Y pass
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation fail
3' LR-PCR -
ES Cell Clones Without Conditional Potential

No clones available.

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
359949 PG00236_Z_8_B05 PCS00236_A_H07 L1L2_Bact_P L3L4_pD223_DTA_T_spec view
Vectors ES Cells
KOMP-Regeneron
(Project: VG18100)
order order view details

ES Cell Clones

Cassette Type 0 Knockout-First Alleles 2 Targeted Non-Conditional Alleles
Promotor Driven
Targeting Vector: genbank file
Allele: genbank file
Targeting Vector: genbank file
ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
18100A-C12 VG18100 C57BL/6NTac VGB6 tm1(KOMP)Vlcg Reporter-Tagged Deletion (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen - LoxP Screen - 3' Screen -
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
18100A-C7 VG18100 C57BL/6NTac VGB6 tm1(KOMP)Vlcg Reporter-Tagged Deletion (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen - LoxP Screen - 3' Screen -
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
VG18100 ZEN-Ub1 view
Vectors ES Cells
EUCOMMTools
(Project: 125629)
currently unavailable currently unavailable view details

ES Cell Clones

Cassette Type 2 Knockout-First Alleles 2 Targeted Non-Conditional Alleles
Promotor Driven
Allele: genbank file | image
Targeting Vector: genbank file | image
Allele: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
HEPD0881_3_E01 PG00236_Z_8_B05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(EUCOMM)Hmgu Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen pass 3' Screen not confirmed
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
HEPD0881_3_G01 PG00236_Z_8_B05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(EUCOMM)Hmgu Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen pass 3' Screen not confirmed
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
ES Cell Clones Without Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
HEPD0881_3_B05 PG00236_Z_8_B05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Hmgu Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen - LoxP Screen - 3' Screen -
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
HEPD0881_3_D06 PG00236_Z_8_B05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Hmgu Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen - LoxP Screen - 3' Screen -
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
359949 PG00236_Z_8_B05 PCS00236_A_H07 L1L2_Bact_P L3L4_pD223_DTA_T_spec view
359949 PG00236_Z_8_B05 PCS00236_A_H07 L1L2_Bact_P L3L4_pD223_DTA_T_spec view
Vectors ES Cells
NorCOMM
Design Completed Projects: 42500, 41493

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
23 5 1 1 view in Ensembl

Ube2w

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube2w was found for the following reasons:
colony_prefix - Ube2w EPD0156_4_D07
marker_name - ubiquitin-conjugating enzyme E2W (putative)
symbol - Ube2w
interpro_desc - UBQ-conjugating_enzyme/RWD
marker_symbol_str - Ube2w
marker_symbol - Ube2w
interpro - IPR000608||UBQ-conjugat_E2||Ubiquitin-conjugating enzyme, E2

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
20 1 0 0 view in Ensembl

Ube2z

Ube2z was found for the following reasons:
marker_name - ubiquitin-conjugating enzyme E2Z (putative)
symbol - Ube2z
interpro_desc - UBQ-conjugating_enzyme/RWD
marker_symbol_str - Ube2z
marker_symbol - Ube2z
interpro - IPR000608||UBQ-conjugat_E2||Ubiquitin-conjugating enzyme, E2

Gene Details

Marker Name(s): ubiquitin-conjugating enzyme E2Z (putative)
view this gene in MGI
Marker Type: protein coding gene
Synonyms: AW049199, C030047H17Rik, D11Moh35
Location: Chr11:96047432-96065388(-)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:1343160 Ensembl Gene ID: ENSMUSG00000014349 Vega Gene ID: OTTMUSG00000001958
Entrez Gene ID: 268470 CCDS ID:
Interpro Families
Orthologs / Homologs
Species Marker Symbol Entrez Gene ID Ensembl Gene ID
Human UBE2Z 65264
Rat Ube2z 303478

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
Vector Unsuccessful - Project Terminated Projects: 26960, 26959
Vectors ES Cells
NorCOMM
Vector Construction in Progress Projects: 71247

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
15 5 2 0 view in Ensembl

Ube3a

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube3a was found for the following reasons:
synonym - E6-AP ubiquitin protein ligase
marker_name - ubiquitin protein ligase E3A
symbol - Ube3a
interpro_desc - Ubiquitin-protein_ligase_E6-AP
marker_symbol_str - Ube3a
marker_symbol - Ube3a
interpro - IPR017134||Ubiquitin-protein_ligase_E6-AP||Ubiquitin-protein ligase E6-AP

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
17 6 0 0 view in Ensembl

Ube3b

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube3b was found for the following reasons:
marker_name - ubiquitin protein ligase E3B
symbol - Ube3b
marker_symbol_str - Ube3b
marker_symbol - Ube3b

Gene Details no data available

WTSI Phenotyping

MP Ontology Based Heatmap
Allele Name Colony Prefix Colony Strain adipose tissue behavior/neurological cardiovascular system cellular craniofacial digestive/alimentary embryogenesis endocrine/exocrine gland growth/size hearing/vestibular/ear hematopoietic system homeostasis/metabolism immune system integument limbs/digits/tail liver/biliary system mortality/aging muscle nervous system other pigmentation renal/urinary system reproductive system respiratory system skeleton taste/olfaction tumorigenesis vision/eye
Ube3b MHKN view view view view view view view view view view view view view view view view view view view view
Legend: No Raw Data No Significant Annotations Significant Annotation Present Link to a Test Report Page Link to a test report page
About This Heatmap

This heatmap is built up of top-level terms from the MP (Mammalian Phenotype) ontology. We have mapped a majority of the parameters in our tests to appropriate MP terms, so when we perform a given test we can say if it should be annotated with the given MP term (if the phenotype is significant). This is what you see in this heatmap - if a significant result has been annotated to a top-level MP term (or any of its children), the cell will be red, if the result was not significant, the cell will be blue.

Please Note: as mentioned above we do not annotate all of our phenotyping tests to the MP ontology. The tests that are excluded are: 'Adult LacZ Expression', 'Brain/Eye/Skin Histopathology', 'Embryo LacZ Expression', 'Fertility', 'Heart Histology', 'Micronuclei', 'MicroCT & Quantitative Faxitron', 'Plasma Immunoglobulins', 'Prepulse Inhibition', 'Recessive Lethal Study', 'Tail Epidermis Wholemount', 'Tissue Biobank' and 'Viability at Weaning'. You can find our results for these tests in the 'Phenotyping Test Based Heatmap' below.

Phenotyping Test Based Heatmap
Allele Name Colony Prefix Colony Strain Viability at weaning Recessive Lethal Study Fertility Embryo LacZ Expression Adult LacZ Expression General Observations Weight Curves Open Field Modified SHIRPA Grip Strength Hot Plate Dysmorphology Rotarod Non-Invasive Blood Pressure Prepulse Inhibition Indirect Calorimetry Glucose Tolerance (ip) Auditory Brainstem Response Body Composition (DEXA) X-ray Imaging Stress Induced Hyperthermia Eye Morphology Plasma Chemistry Plasma Immunoglobulins Haematology (CBC) Peripheral Blood Lymphocytes Micronuclei Tissue Biobank Heart Weight Heart Histology Tail Epidermis Wholemount Skin Histopathology Brain Histopathology Eye Histopathology MicroCT & Quantitative Faxitron Salmonella Challenge Citrobacter Challenge
Ube3b MHKN view view view view view view view view view view view view view view view view view view view view view view view view view view view view view view view
download a spreadsheet containing all WTSI phenotyping data
Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned Link to a Test Report Page Link to a test report page Link to a PDF Report Link to a pdf report

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
12 6 0 0 view in Ensembl

Ube3c

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube3c was found for the following reasons:
marker_name - ubiquitin protein ligase E3C
symbol - Ube3c
marker_symbol_str - Ube3c
marker_symbol - Ube3c

Gene Details no data available

WTSI Phenotyping no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
40 5 7 0 view in Ensembl

Ube4a

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube4a was found for the following reasons:
synonym - UFD2b
marker_name - ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)
symbol - Ube4a
interpro_desc - Ub_conjug_fac_E4_core
marker_symbol_str - Ube4a
marker_symbol - Ube4a
interpro - IPR019474||Ub_conjug_fac_E4_core||Ubiquitin conjugation factor E4, core

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
25 12 1 0 view in Ensembl

Ube4b

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Ube4b was found for the following reasons:
synonym - Ufd2p
marker_name - ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
symbol - Ube4b
interpro_desc - Ub_conjug_fac_E4_core
marker_symbol_str - Ube4b
marker_symbol - Ube4b
interpro - IPR019474||Ub_conjug_fac_E4_core||Ubiquitin conjugation factor E4, core

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
32 17 4 0 view in Ensembl