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Mammalian Phenotype
Chromosome
Marker Symbol

Browsing Data by Marker Symbol: 'P'

Pus7l

Pus7l was found for the following reasons:
marker_name - pseudouridylate synthase 7 homolog (S. cerevisiae)-like
symbol - Pus7l
interpro_desc - PsdUridine_synth_cat_dom
targeting_vector - PG00036_W_1_E06
marker_symbol_str - Pus7l
marker_symbol - Pus7l
ma_term - postnatal mouse
intermediate_vector - PCS00036_A_E06
mp_ontology - vision/eye phenotype | abnormal eye morphology | pigmentation phenotype | abnormal posterior eye
marker_type - protein coding gene
ma_ontology - anatomical structure | postnatal mouse | anatomic region | organ system | trunk | visceral organ
mp_term - pigmentation phenotype
interpro - IPR020103||PsdUridine_synth_cat_dom||Pseudouridine synthase, catalytic domain

Gene Details

Marker Name(s): pseudouridylate synthase 7 homolog (S. cerevisiae)-like
view this gene in MGI
Marker Type: protein coding gene
Synonyms: 3000003F02Rik
Location: Chr15:94522688-94543547(-)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:1926145 Ensembl Gene ID: ENSMUSG00000033356 Vega Gene ID: OTTMUSG00000023451
Entrez Gene ID: 78895 CCDS ID:

WTSI Phenotyping

MP Ontology Based Heatmap
Allele Name Colony Prefix Colony Strain adipose tissue behavior/neurological cardiovascular system cellular craniofacial digestive/alimentary embryogenesis endocrine/exocrine gland growth/size hearing/vestibular/ear hematopoietic system homeostasis/metabolism immune system integument limbs/digits/tail liver/biliary system mortality/aging muscle nervous system other pigmentation renal/urinary system reproductive system respiratory system skeleton taste/olfaction tumorigenesis vision/eye
Pus7ltm2a(KOMP)Wtsi MBJW C57BL/6NTac;C57BL/6NTac;C57BL/6N view view view view view view view view view view view view view view view view view view view view
Legend: No Raw Data No Significant Annotations Significant Annotation Present Link to a Test Report Page Link to a test report page
About This Heatmap

This heatmap is built up of top-level terms from the MP (Mammalian Phenotype) ontology. We have mapped a majority of the parameters in our tests to appropriate MP terms, so when we perform a given test we can say if it should be annotated with the given MP term (if the phenotype is significant). This is what you see in this heatmap - if a significant result has been annotated to a top-level MP term (or any of its children), the cell will be red, if the result was not significant, the cell will be blue.

Please Note: as mentioned above we do not annotate all of our phenotyping tests to the MP ontology. The tests that are excluded are: 'Adult LacZ Expression', 'Brain/Eye/Skin Histopathology', 'Embryo LacZ Expression', 'Fertility', 'Heart Histology', 'Micronuclei', 'MicroCT & Quantitative Faxitron', 'Plasma Immunoglobulins', 'Prepulse Inhibition', 'Recessive Lethal Study', 'Tail Epidermis Wholemount', 'Tissue Biobank' and 'Viability at Weaning'. You can find our results for these tests in the 'Phenotyping Test Based Heatmap' below.

Phenotyping Test Based Heatmap
Allele Name Colony Prefix Colony Strain Viability at weaning Recessive Lethal Study Fertility Embryo LacZ Expression Adult LacZ Expression General Observations Weight Curves Open Field Modified SHIRPA Grip Strength Hot Plate Dysmorphology Rotarod Non-Invasive Blood Pressure Prepulse Inhibition Indirect Calorimetry Glucose Tolerance (ip) Auditory Brainstem Response Body Composition (DEXA) X-ray Imaging Stress Induced Hyperthermia Eye Morphology Plasma Chemistry Plasma Immunoglobulins Haematology (CBC) Peripheral Blood Lymphocytes Micronuclei Tissue Biobank Heart Weight Heart Histology Tail Epidermis Wholemount Skin Histopathology Brain Histopathology Eye Histopathology MicroCT & Quantitative Faxitron Salmonella Challenge Citrobacter Challenge
Pus7ltm2a(KOMP)Wtsi MBJW C57BL/6NTac;C57BL/6NTac;C57BL/6N view view view view view view view view view view view view view view view view view view view view view view view view view view pdf view view
download a spreadsheet containing all WTSI phenotyping data
Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned Link to a Test Report Page Link to a test report page Link to a PDF Report Link to a pdf report

Mice

Allele Name Allele Type EMMA ID Colony Prefix ES Cell/Common Name Genetic Background QC/Screening Data MI/Distribution Centre
contact distributor Pus7ltm2a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) MBJW EPD0085_6_H01 C57BL/6NTac;C57BL/6NTac;C57BL/6N view data
about )
WTSI/KOMP Repo
Southern Blot na TV Backbone Assay pass 5' LR-PCR pass
Loss of WT Allele (LOA) qPCR na Homozygous Loss of WT Allele (LOA) SR-PCR pass Neo Count (qPCR) pass
LacZ SR-PCR pass 5' Cassette Integrity Neo SR-PCR na
Mutant Specific SR-PCR pass LoxP Confirmation pass 3' LR-PCR na
Genotyping Comment

IKMC Vectors and ES Cells

Vectors ES Cells
KOMP-CSD
(Project: 33819)
order order view details

ES Cell Clones

Cassette Type 1 Knockout-First Alleles 0 Targeted Non-Conditional Alleles
Promotor Driven
Allele: genbank file | image
Targeting Vector: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
EPD0085_6_H01 PRPGS00036_C_E06 C57BL/6N JM8.F6 tm2a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not attempted LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) fail Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR pass 5' SR-PCR - 3' SR-PCR pass
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
ES Cell Clones Without Conditional Potential

No clones available.

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
42133 PRPGS00036_C_E06 PCS00036_A_E06 L1L2_Bact_P L4L3_pD223_DTA_spec view

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
25 8 1 3 view in Ensembl

Pusl1

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pusl1 was found for the following reasons:
marker_name - pseudouridylate synthase-like 1
symbol - Pusl1
interpro_desc - PsdUridine_synth_cat_dom
targeting_vector - PG00142_Y_3_D05
marker_symbol_str - Pusl1
marker_symbol - Pusl1
intermediate_vector - PCS00142_A_D05
marker_type - protein coding gene
interpro - IPR020103||PsdUridine_synth_cat_dom||Pseudouridine synthase, catalytic domain

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
20 3 1 0 view in Ensembl

Pv

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pv was found for the following reasons:
marker_name - pivoter
symbol - Pv
marker_symbol_str - Pv
marker_symbol - Pv
marker_type - heritable phenotypic marker

Gene Details

Marker Name(s): pivoter
view this gene in MGI
Marker Type: heritable phenotypic marker
Synonyms:
Location: ChrUN
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:97820 Ensembl Gene ID: Vega Gene ID:
Entrez Gene ID: 103932 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

Pvalb

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pvalb was found for the following reasons:
synonym - PV
marker_name - parvalbumin
symbol - Pvalb
targeting_vector - N00055P1_T_1-67.4_E07
marker_symbol_str - Pvalb
escell - N00055P1_C_260W_C10
marker_symbol - Pvalb
intermediate_vector - N00055P1_I_1-67.4_E07

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
28 9 0 0 view in Ensembl

Pvr

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pvr was found for the following reasons:
marker_name - poliovirus receptor
symbol - Pvr
marker_symbol_str - Pvr
marker_symbol - Pvr
intermediate_vector - PCS6006_A_B09
marker_type - protein coding gene

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
25 7 0 0 view in Ensembl

Pvrig-ps

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pvrig-ps was found for the following reasons:
synonym - Pvrig
marker_name - poliovirus receptor related immunoglobulin domain containing, pseudogene
symbol - Pvrig-ps
marker_symbol_str - Pvrig-ps
marker_symbol - Pvrig-ps

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

Pvrl1

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pvrl1 was found for the following reasons:
synonym - PRR
marker_name - poliovirus receptor-related 1
symbol - Pvrl1
targeting_vector - PG00252_Z_6_H02
marker_symbol_str - Pvrl1
marker_symbol - Pvrl1
intermediate_vector - PCS00252_A_F11
marker_type - protein coding gene

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
28 5 2 0 view in Ensembl

Pvrl2

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pvrl2 was found for the following reasons:
synonym - Pvr
marker_name - poliovirus receptor-related 2
symbol - Pvrl2
targeting_vector - PG00181_Z_6_C10
marker_symbol_str - Pvrl2
marker_symbol - Pvrl2
intermediate_vector - PCS00181_A_C10

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
27 9 1 0 view in Ensembl

Pvrl3

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Pvrl3 was found for the following reasons:
marker_name - poliovirus receptor-related 3
symbol - Pvrl3
targeting_vector - PRPGS00071_A_A10
marker_symbol_str - Pvrl3
marker_symbol - Pvrl3
intermediate_vector - PCS00071_A_A10
marker_type - protein coding gene

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
33 10 1 0 view in Ensembl

Pvrl4

Pvrl4 was found for the following reasons:
synonym - Prr4
marker_name - poliovirus receptor-related 4
symbol - Pvrl4
marker_symbol_str - Pvrl4
marker_symbol - Pvrl4
marker_type - protein coding gene

Gene Details

Marker Name(s): poliovirus receptor-related 4
view this gene in MGI
Marker Type: protein coding gene
Synonyms: 1200017F15Rik, Prr4, nectin 4
Location: Chr1:171370099-171388598(+)
Related Human Conditions (from OMIM) - no related Human Condition
More Information

WTSI Phenotyping no data available

Mice no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
23 11 1 0 view in Ensembl