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Mammalian Phenotype
Chromosome
Marker Symbol

Browsing Data by Marker Symbol: 'H'

H2-D2

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
H2-D2 was found for the following reasons:
synonym - H-2D2
marker_name - histocompatibility 2, D region locus 2
symbol - H2-D2
marker_symbol_str - H2-D2
marker_symbol - H2-D2

Gene Details

Marker Name(s): histocompatibility 2, D region locus 2
view this gene in MGI
Marker Type: protein coding gene
Synonyms: H-2D2
Location: Chr17
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95897 Ensembl Gene ID: Vega Gene ID:
Entrez Gene ID: 110536 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

H2-D3

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
H2-D3 was found for the following reasons:
synonym - H-2D3
marker_name - histocompatibility 2, D region locus 3
symbol - H2-D3
marker_symbol_str - H2-D3
marker_symbol - H2-D3

Gene Details

Marker Name(s): histocompatibility 2, D region locus 3
view this gene in MGI
Marker Type: protein coding gene
Synonyms: H-2D3
Location: Chr17
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95898 Ensembl Gene ID: Vega Gene ID:
Entrez Gene ID: 110553 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

H2-D4

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
H2-D4 was found for the following reasons:
synonym - H-2D4
marker_name - histocompatibility 2, D region locus 4
symbol - H2-D4
marker_symbol_str - H2-D4
marker_symbol - H2-D4

Gene Details

Marker Name(s): histocompatibility 2, D region locus 4
view this gene in MGI
Marker Type: pseudogene
Synonyms: H-2D4
Location: Chr17
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95899 Ensembl Gene ID: Vega Gene ID:
Entrez Gene ID: 14967 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

H2-DMa

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
H2-DMa was found for the following reasons:
synonym - H-2Ma
marker_name - histocompatibility 2, class II, locus DMa
symbol - H2-DMa
targeting_vector - HTGR04008_Z_6_G02
marker_symbol_str - H2-DMa
marker_symbol - H2-DMa

Gene Details

Marker Name(s): histocompatibility 2, class II, locus DMa
view this gene in MGI
Marker Type: protein coding gene
Synonyms: H-2Ma, H2-M alpha, H2-Ma
Location: Chr17:34135182-34139101(+)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95921 Ensembl Gene ID: ENSMUSG00000037649 Vega Gene ID: OTTMUSG00000037115
Entrez Gene ID: 14998 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
(Project: 81434)
order order view details

ES Cell Clones

Cassette Type 0 Knockout-First Alleles 2 Targeted Non-Conditional Alleles
Promotor Driven
Targeting Vector: genbank file | image
Allele: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
EPD0749_2_D04 HTGR04008_Z_6_G02 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not attempted LoxP Screen not confirmed 3' Screen pass
Loss of WT Allele (LOA) fail Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0749_2_F04 HTGR04008_Z_6_G02 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not attempted LoxP Screen not confirmed 3' Screen pass
Loss of WT Allele (LOA) fail Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
115569 HTGR04008_Z_6_G02 PCS04008_A_F02 L1L2_Bact_P L3L4_pD223_DTA_T_spec view
Vectors ES Cells
NorCOMM
VEGA Annotation Requested Projects: 49083

DNA Clone Resources no data available

H2-DMb1

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
H2-DMb1 was found for the following reasons:
synonym - H2-M beta1
marker_name - histocompatibility 2, class II, locus Mb1
symbol - H2-DMb1
targeting_vector - PG00193_Z_1_H03
marker_symbol_str - H2-DMb1
marker_symbol - H2-DMb1

Gene Details

Marker Name(s): histocompatibility 2, class II, locus Mb1
view this gene in MGI
Marker Type: protein coding gene
Synonyms: AI385589, H-2Mb1, H2-M beta1, H2-Mb1
Location: Chr17:34153072-34160223(+)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95922 Ensembl Gene ID: ENSMUSG00000079547 Vega Gene ID: OTTMUSG00000037116
Entrez Gene ID: 14999 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
(Project: 69021)
order order view details

ES Cell Clones

Cassette Type 0 Knockout-First Alleles 5 Targeted Non-Conditional Alleles
Promotor Driven
Targeting Vector: genbank file | image
Allele: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential

No clones available.

ES Cell Clones Without Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
EPD0546_8_B10 PG00193_Z_1_C08 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen not confirmed 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0546_8_B12 PG00193_Z_1_C08 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen not confirmed 3' Screen not confirmed
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0546_8_C11 PG00193_Z_1_C08 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen not confirmed 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0546_8_F10 PG00193_Z_1_C08 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen not confirmed 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0546_8_G09 PG00193_Z_1_C08 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(EUCOMM)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen not confirmed 3' Screen not confirmed
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
244125 PG00193_Z_1_C08 PCS00193_A_A06 L1L2_Bact_P L3L4_pD223_DTA_T_spec view

DNA Clone Resources no data available

H2-DMb2

H2-DMb2 was found for the following reasons:
synonym - H2-Mb2
marker_name - histocompatibility 2, class II, locus Mb2
symbol - H2-DMb2
marker_symbol_str - H2-DMb2
marker_symbol - H2-DMb2

Gene Details

Marker Name(s): histocompatibility 2, class II, locus Mb2
view this gene in MGI
Marker Type: protein coding gene
Synonyms: H-2Mb2, H2-M beta2, H2-Mb2
Location: Chr17:34143307-34151553(+)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95923 Ensembl Gene ID: ENSMUSG00000037548 Vega Gene ID: OTTMUSG00000037091
Entrez Gene ID: 15000 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
23 7 0 0 view in Ensembl

H2-Ea-ps

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
H2-Ea-ps was found for the following reasons:
synonym - H-2Ea
marker_name - histocompatibility 2, class II antigen E alpha, pseudogene
symbol - H2-Ea-ps
marker_symbol_str - H2-Ea-ps
marker_symbol - H2-Ea-ps

Gene Details

Marker Name(s): histocompatibility 2, class II antigen E alpha, pseudogene
view this gene in MGI
Marker Type: pseudogene
Synonyms: AI323765, H-2Ea, I-Ealpha, Ia-3, Ia3
Location: Chr17:34342933-34344643(-)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95900 Ensembl Gene ID: ENSMUSG00000036322 Vega Gene ID: OTTMUSG00000020170
Entrez Gene ID: 100504404 CCDS ID:
Orthologs / Homologs
Species Marker Symbol Entrez Gene ID Ensembl Gene ID
Human HLA-DRA 3122
Rat RT1-Da 294269

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
KOMP-CSD
Withdrawn From Pipeline Projects: 38369
Vectors ES Cells
NorCOMM
VEGA Annotation Requested Projects: 49088

DNA Clone Resources no data available

H2-Eb1

H2-Eb1 was found for the following reasons:
synonym - H-2Eb
marker_name - histocompatibility 2, class II antigen E beta
symbol - H2-Eb1
targeting_vector - HTGRS6006_B_H05
marker_symbol_str - H2-Eb1
escell - EPD0614_1_H09
marker_symbol - H2-Eb1
intermediate_vector - PCS6006_B_H05

Gene Details

Marker Name(s): histocompatibility 2, class II antigen E beta
view this gene in MGI
Marker Type: protein coding gene
Synonyms: H-2Eb, Ia-4, Ia4
Location: Chr17:34305883-34316199(+)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95901 Ensembl Gene ID: ENSMUSG00000060586 Vega Gene ID: OTTMUSG00000037123
Entrez Gene ID: 14969 CCDS ID:

WTSI Phenotyping

MP Ontology Based Heatmap
Allele Name Colony Prefix Colony Strain adipose tissue behavior/neurological cardiovascular system cellular craniofacial digestive/alimentary embryogenesis endocrine/exocrine gland growth/size hearing/vestibular/ear hematopoietic system homeostasis/metabolism immune system integument limbs/digits/tail liver/biliary system mortality/aging muscle nervous system other pigmentation renal/urinary system reproductive system respiratory system skeleton taste/olfaction tumorigenesis vision/eye
H2-Eb1tm1a(KOMP)Wtsi MFEH C57BL/6NTac;C57BL/6NTac;C57BL/6N-Atm1Brd/a view view view view view view view view view view view view view view view view view
Legend: No Raw Data No Significant Annotations Significant Annotation Present Link to a Test Report Page Link to a test report page
About This Heatmap

This heatmap is built up of top-level terms from the MP (Mammalian Phenotype) ontology. We have mapped a majority of the parameters in our tests to appropriate MP terms, so when we perform a given test we can say if it should be annotated with the given MP term (if the phenotype is significant). This is what you see in this heatmap - if a significant result has been annotated to a top-level MP term (or any of its children), the cell will be red, if the result was not significant, the cell will be blue.

Please Note: as mentioned above we do not annotate all of our phenotyping tests to the MP ontology. The tests that are excluded are: 'Adult LacZ Expression', 'Brain/Eye/Skin Histopathology', 'Embryo LacZ Expression', 'Fertility', 'Heart Histology', 'Micronuclei', 'MicroCT & Quantitative Faxitron', 'Plasma Immunoglobulins', 'Prepulse Inhibition', 'Recessive Lethal Study', 'Tail Epidermis Wholemount', 'Tissue Biobank' and 'Viability at Weaning'. You can find our results for these tests in the 'Phenotyping Test Based Heatmap' below.

Phenotyping Test Based Heatmap
Allele Name Colony Prefix Colony Strain Viability at weaning Recessive Lethal Study Fertility Embryo LacZ Expression Adult LacZ Expression General Observations Weight Curves Open Field Modified SHIRPA Grip Strength Hot Plate Dysmorphology Rotarod Non-Invasive Blood Pressure Prepulse Inhibition Indirect Calorimetry Glucose Tolerance (ip) Auditory Brainstem Response Body Composition (DEXA) X-ray Imaging Stress Induced Hyperthermia Eye Morphology Plasma Chemistry Plasma Immunoglobulins Haematology (CBC) Peripheral Blood Lymphocytes Micronuclei Tissue Biobank Heart Weight Heart Histology Tail Epidermis Wholemount Skin Histopathology Brain Histopathology Eye Histopathology MicroCT & Quantitative Faxitron Salmonella Challenge Citrobacter Challenge
H2-Eb1tm1a(KOMP)Wtsi MFEH C57BL/6NTac;C57BL/6NTac;C57BL/6N-Atm1Brd/a view view view view view view view view view view view view view view view view
download a spreadsheet containing all WTSI phenotyping data
Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned Link to a Test Report Page Link to a test report page Link to a PDF Report Link to a pdf report

Mice

Allele Name Allele Type EMMA ID Colony Prefix ES Cell/Common Name Genetic Background QC/Screening Data MI/Distribution Centre
contact distributor H2-Eb1tm1a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) MFEH EPD0614_1_C10 C57BL/6NTac;C57BL/6NTac;C57BL/6N-Atm1Brd/a view data
about )
WTSI
Southern Blot na TV Backbone Assay pass 5' LR-PCR na
Loss of WT Allele (LOA) qPCR pass Homozygous Loss of WT Allele (LOA) SR-PCR pass Neo Count (qPCR) pass
LacZ SR-PCR pass 5' Cassette Integrity Neo SR-PCR na
Mutant Specific SR-PCR pass LoxP Confirmation pass 3' LR-PCR na
Genotyping Comment

IKMC Vectors and ES Cells

Vectors ES Cells
KOMP-CSD
(Project: 80297)
order order view details

ES Cell Clones

Cassette Type 2 Knockout-First Alleles 3 Targeted Non-Conditional Alleles
Promotor Driven
Allele: genbank file | image
Targeting Vector: genbank file | image
Allele: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
EPD0614_1_C10 HTGRS6006_B_H05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen pass 3' Screen not confirmed
Loss of WT Allele (LOA) pass Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA pass LOXP pass LACZ pass
Chromosome 1 pass Chromosome 8a pass Chromosome 8b -
Chromosome 11a pass Chromosome 11b pass Chromosome Y pass
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0614_1_F11 HTGRS6006_B_H05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen pass 3' Screen not confirmed
Loss of WT Allele (LOA) pass Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
ES Cell Clones Without Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
EPD0614_1_A11 HTGRS6006_B_H05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(KOMP)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen no reads detected LoxP Screen no reads detected 3' Screen no reads detected
Loss of WT Allele (LOA) pass Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0614_1_D10 HTGRS6006_B_H05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(KOMP)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen not confirmed 3' Screen not confirmed
Loss of WT Allele (LOA) pass Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0614_1_H09 HTGRS6006_B_H05 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1e(KOMP)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen not confirmed 3' Screen not confirmed
Loss of WT Allele (LOA) pass Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
82799 HTGRS6006_B_H05 PCS6006_B_H05 L1L2_Bact_P R3R4_pBR_DTA+_Bsd_amp view
82799 HTGRS6006_B_H05 PCS6006_B_H05 L1L2_Bact_P R3R4_pBR_DTA+_Bsd_amp view
Vectors ES Cells
KOMP-Regeneron
Design Not Possible Projects: VG15227

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
25 6 2 2 view in Ensembl

H2-Eb2

H2-Eb2 was found for the following reasons:
synonym - H-2Eb2
marker_name - histocompatibility 2, class II antigen E beta2
symbol - H2-Eb2
microinjection_centre - Harwell
targeting_vector - PG00234_Z_6_H04
marker_symbol_str - H2-Eb2
escell - HEPD0777_1_G05
marker_symbol - H2-Eb2
allele - tm1a(EUCOMM)Hmgu

Gene Details

Marker Name(s): histocompatibility 2, class II antigen E beta2
view this gene in MGI
Marker Type: protein coding gene
Synonyms: A130038H09Rik, H-2Eb2, Ia-5, Ia5
Location: Chr17:34325665-34340229(+)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95902 Ensembl Gene ID: ENSMUSG00000067341 Vega Gene ID: OTTMUSG00000020169
Entrez Gene ID: 381091 CCDS ID:

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
(Project: 86988)
order order view details

ES Cell Clones

Cassette Type 3 Knockout-First Alleles 0 Targeted Non-Conditional Alleles
Promotor Driven
Allele: genbank file | image
Targeting Vector: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
HEPD0777_1_G05 PG00234_Z_6_G02 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(EUCOMM)Hmgu Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen pass 3' Screen not confirmed
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0788_4_E05 PG00234_Z_6_H04 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(EUCOMM)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not attempted LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0788_4_F08 PG00234_Z_6_H04 C57BL/6N-Atm1Brd/a JM8A3.N1 tm1a(EUCOMM)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not attempted LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
ES Cell Clones Without Conditional Potential

No clones available.

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
356188 PG00234_Z_6_H04 PCS00234_A_F05 L1L2_Bact_P L3L4_pD223_DTA_T_spec view
356188 PG00234_Z_6_G02 PCS00234_A_F05 L1L2_Bact_P L3L4_pD223_DTA_T_spec view
Vectors ES Cells
KOMP-Regeneron
Design Not Possible Projects: VG11378

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
27 9 0 2 view in Ensembl

H2-K1

H2-K1 was found for the following reasons:
synonym - H-2K
marker_name - histocompatibility 2, K1, K region
symbol - H2-K1
marker_symbol_str - H2-K1
marker_symbol - H2-K1

Gene Details

Marker Name(s): histocompatibility 2, K1, K region
view this gene in MGI
Marker Type: protein coding gene
Synonyms: H-2K
Location: Chr17:33996017-34000333(-)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:95904 Ensembl Gene ID: ENSMUSG00000061232 Vega Gene ID: OTTMUSG00000037104
Entrez Gene ID: 14972 CCDS ID:
Interpro Families
Orthologs / Homologs
Species Marker Symbol Entrez Gene ID Ensembl Gene ID
Human HLA-B 3106
Rat RT1-A1 24973
Rat RT1-A2 24974
Rat RT1-A3 309627
Rat RT1-CE1 309603
Rat RT1-CE10 414792
Rat RT1-CE11 414791
Rat RT1-CE12 309600
Rat RT1-CE13 414790
Rat RT1-CE15 414789
Rat RT1-CE16 414819
Rat RT1-CE2 414779
Rat RT1-CE3 414793
Rat RT1-CE4 414783
Rat RT1-CE5 309607
Rat RT1-CE7 368153
Rat RT1-Cl 24977

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
Withdrawn From Pipeline Projects: 98526
Vectors ES Cells
NorCOMM
Design Requested Projects: 66191

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
32 10 0 0 view in Ensembl