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Mammalian Phenotype
Chromosome
Marker Symbol

Browsing Data by Marker Symbol: 'A'

Atxn2

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn2 was found for the following reasons:
synonym - ATX2
ikmc_project_product_status - KOMP-CSD Vector Available
marker_name - ataxin 2
symbol - Atxn2
interpro_desc - LsmAD_domain
targeting_vector - PG00100_W_4_A05
marker_symbol_str - Atxn2
escell - EPD0238_1_A01
marker_symbol - Atxn2
product_status - Vector Available
intermediate_vector - PCS00100_A_A05
allele - tm1a(KOMP)Wtsi
ikmc_project_id - IST10565A4
interpro - IPR009604||LsmAD_domain||LsmAD domain

Gene Details no data available

WTSI Phenotyping no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
37 11 5 0 view in Ensembl

Atxn2l

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn2l was found for the following reasons:
synonym - A2lp
colony_prefix - Atxn2l
ikmc_project_product_status - EUCOMM Vector Available
marker_name - ataxin 2-like
symbol - Atxn2l
interpro_desc - LsmAD_domain
targeting_vector - PG00215_Z_8_A09
marker_symbol_str - Atxn2l
marker_symbol - Atxn2l
product_status - Vector Available
intermediate_vector - PCS00215_A_F10
allele - tm1a(EUCOMM)Hmgu
interpro - IPR009604||LsmAD_domain||LsmAD domain

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
21 11 0 0 view in Ensembl

Atxn3

Atxn3 was found for the following reasons:
synonym - ataxin-3
ikmc_project_product_status - KOMP-CSD Vector Available
sanger_phenotype - viability_at_weaning
marker_name - ataxin 3
symbol - Atxn3
phenotype - viability_at_weaning
targeting_vector - PRPGS00078_A_B02
marker_symbol_str - Atxn3
marker_symbol - Atxn3
product_status - Vector Available
intermediate_vector - PCS00078_A_B02
mp_ontology - mortality/aging | abnormal survival | partial lethality
allele - tm1a(KOMP)Wtsi
mp_term - mortality/aging

Gene Details

Marker Name(s): ataxin 3
view this gene in MGI
Marker Type: protein coding gene
Synonyms: 2210008M02Rik, AI463012, AI647473, Atx3, MJD1, Mjd, Sca3, ataxin-3
Location: Chr12:101918901-101958246(-)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:1099442 Ensembl Gene ID: ENSMUSG00000021189 Vega Gene ID: OTTMUSG00000030696
Entrez Gene ID: 110616 CCDS ID:
Interpro Families
Orthologs / Homologs
Species Marker Symbol Entrez Gene ID Ensembl Gene ID
Human ATXN3 4287
Rat Atxn3 60331

WTSI Phenotyping

MP Ontology Based Heatmap
Allele Name Colony Prefix Colony Strain adipose tissue behavior/neurological cardiovascular system cellular craniofacial digestive/alimentary embryogenesis endocrine/exocrine gland growth/size hearing/vestibular/ear hematopoietic system homeostasis/metabolism immune system integument limbs/digits/tail liver/biliary system mortality/aging muscle nervous system other pigmentation renal/urinary system reproductive system respiratory system skeleton taste/olfaction tumorigenesis vision/eye
Atxn3tm1a(KOMP)Wtsi MGEK C57BL/6NTac;C57BL/6NTac;C57BL/6N view view view
Legend: No Raw Data No Significant Annotations Significant Annotation Present Link to a Test Report Page Link to a test report page
About This Heatmap

This heatmap is built up of top-level terms from the MP (Mammalian Phenotype) ontology. We have mapped a majority of the parameters in our tests to appropriate MP terms, so when we perform a given test we can say if it should be annotated with the given MP term (if the phenotype is significant). This is what you see in this heatmap - if a significant result has been annotated to a top-level MP term (or any of its children), the cell will be red, if the result was not significant, the cell will be blue.

Please Note: as mentioned above we do not annotate all of our phenotyping tests to the MP ontology. The tests that are excluded are: 'Adult LacZ Expression', 'Brain/Eye/Skin Histopathology', 'Embryo LacZ Expression', 'Fertility', 'Heart Histology', 'Micronuclei', 'MicroCT & Quantitative Faxitron', 'Plasma Immunoglobulins', 'Prepulse Inhibition', 'Recessive Lethal Study', 'Tail Epidermis Wholemount', 'Tissue Biobank' and 'Viability at Weaning'. You can find our results for these tests in the 'Phenotyping Test Based Heatmap' below.

Phenotyping Test Based Heatmap
Allele Name Colony Prefix Colony Strain Viability at weaning Recessive Lethal Study Fertility Embryo LacZ Expression Adult LacZ Expression General Observations Weight Curves Open Field Modified SHIRPA Grip Strength Hot Plate Dysmorphology Rotarod Non-Invasive Blood Pressure Prepulse Inhibition Indirect Calorimetry Glucose Tolerance (ip) Auditory Brainstem Response Body Composition (DEXA) X-ray Imaging Stress Induced Hyperthermia Eye Morphology Plasma Chemistry Plasma Immunoglobulins Haematology (CBC) Peripheral Blood Lymphocytes Micronuclei Tissue Biobank Heart Weight Heart Histology Tail Epidermis Wholemount Skin Histopathology Brain Histopathology Eye Histopathology MicroCT & Quantitative Faxitron Salmonella Challenge Citrobacter Challenge
Atxn3tm1a(KOMP)Wtsi MGEK C57BL/6NTac;C57BL/6NTac;C57BL/6N view view
download a spreadsheet containing all WTSI phenotyping data
Legend - hover over each heading to get a more complete description
Test complete and data/resources are available Test is complete and the data are considered interesting Preliminary indication of an interesting phenotype
Test is complete but the data are not considered interesting Test not performed or applicable Test pending
Test abandoned Link to a Test Report Page Link to a test report page Link to a PDF Report Link to a pdf report

Mice

Allele Name Allele Type EMMA ID Colony Prefix ES Cell/Common Name Genetic Background QC/Screening Data MI/Distribution Centre
contact distributor Atxn3tm1a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) MGEK EPD0162_1_C04 C57BL/6NTac;C57BL/6NTac;C57BL/6N view data
about )
WTSI/IMG
Southern Blot na TV Backbone Assay pass 5' LR-PCR na
Loss of WT Allele (LOA) qPCR pass Homozygous Loss of WT Allele (LOA) SR-PCR pass Neo Count (qPCR) pass
LacZ SR-PCR pass 5' Cassette Integrity Neo SR-PCR na
Mutant Specific SR-PCR pass LoxP Confirmation pass 3' LR-PCR na
Genotyping Comment

IKMC Vectors and ES Cells

Vectors ES Cells
KOMP-CSD
(Project: 39294)
order order view details

ES Cell Clones

Cassette Type 3 Knockout-First Alleles 2 Targeted Non-Conditional Alleles
Promotor Driven
Allele: genbank file | image
Targeting Vector: genbank file | image
Allele: genbank file | image
Targeting Vector: genbank file | image
ES Cell Clones With Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
EPD0162_1_C02 PRPGS00078_A_B02 C57BL/6N JM8.N4 tm1a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA fail LOXP pass LACZ pass
Chromosome 1 pass Chromosome 8a pass Chromosome 8b -
Chromosome 11a - Chromosome 11b pass Chromosome Y pass
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR pass
EPD0162_1_C04 PRPGS00078_A_B02 C57BL/6N JM8.N4 tm1a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA pass LOXP pass LACZ pass
Chromosome 1 pass Chromosome 8a pass Chromosome 8b -
Chromosome 11a - Chromosome 11b pass Chromosome Y pass
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR pass
EPD0162_1_H03 PRPGS00078_A_B02 C57BL/6N JM8.N4 tm1a(KOMP)Wtsi Knockout First, Reporter-tagged insertion with conditional potential (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen pass 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA pass LOXP pass LACZ pass
Chromosome 1 pass Chromosome 8a pass Chromosome 8b -
Chromosome 11a - Chromosome 11b pass Chromosome Y pass
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
ES Cell Clones Without Conditional Potential
ES Cell Clone Targeting Vector ES Cell Strain ES Cell Line Allele Allele Type QC/Screening Data
EPD0162_1_D02 PRPGS00078_A_B02 C57BL/6N JM8.N4 tm1e(KOMP)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen pass LoxP Screen not confirmed 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -
EPD0162_1_E04 PRPGS00078_A_B02 C57BL/6N JM8.N4 tm1e(KOMP)Wtsi Targeted Non-Conditional (Promotor Driven Cassette) view data    ( about )
Production Centre
5' Screen not confirmed LoxP Screen not confirmed 3' Screen pass
Loss of WT Allele (LOA) - Vector Integrity -
Distribution Centre
Karyotype - Copy Number - Cells Thawed Correctly -
5' LR-PCR - 5' SR-PCR - 3' SR-PCR -
LOA - LOXP - LACZ -
Chromosome 1 - Chromosome 8a - Chromosome 8b -
Chromosome 11a - Chromosome 11b - Chromosome Y -
User/Mouse Clinic
Southern Blot - Map Test - Karyotype -
TV Backbone Assay - 5' LR-PCR - Loss of WT Allele (LOA) -
Neo Count (qPCR) - LacZ SR-PCR - 5' Cassette Integrity -
Neo SR-PCR - Mutant Specific SR-PCR - LoxP Confirmation -
3' LR-PCR -

Targeting Vectors

Design Targeting Vector Intermediate Vector Cassette Backbone Targeting Vector Genbank File
48344 PRPGS00078_A_B02 PCS00078_A_B02 L1L2_Bact_P L3L4_pD223_DTA_spec view
48344 PRPGS00078_A_B02 PCS00078_A_B02 L1L2_Bact_P L3L4_pD223_DTA_spec view

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
20 7 0 2 view in Ensembl

Atxn7

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn7 was found for the following reasons:
synonym - ataxin-7
ikmc_project_product_status - EUCOMM Vector Available
marker_name - ataxin 7
symbol - Atxn7
targeting_vector - PG00191_Z_3_A05
marker_symbol_str - Atxn7
escell - HEPD0654_8_A09
marker_symbol - Atxn7
product_status - Vector Available
intermediate_vector - PCS00191_A_C06
allele - tm1a(EUCOMM)Hmgu

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
30 6 8 0 view in Ensembl

Atxn7l1

Atxn7l1 was found for the following reasons:
synonym - Atxn7l4
ikmc_project_product_status - TIGM ES Cell Available
marker_name - ataxin 7-like 1
symbol - Atxn7l1
marker_symbol_str - Atxn7l1
marker_symbol - Atxn7l1
product_status - ES Cell Available
ikmc_project_id - IST12897A3

Gene Details

Marker Name(s): ataxin 7-like 1
view this gene in MGI
Marker Type: protein coding gene
Synonyms: 2810423G08Rik, Atxn7l4
Location: Chr12:33147693-33375659(+)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:3584458 Ensembl Gene ID: ENSMUSG00000020564 Vega Gene ID: OTTMUSG00000032964
Entrez Gene ID: 380753 CCDS ID:
Interpro Families
Orthologs / Homologs
Species Marker Symbol Entrez Gene ID Ensembl Gene ID
Human ATXN7L1 222255
Rat Atxn7l4 362726

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
Vector - Initial Attempt Unsuccessful Projects: 125297, 97458
Vectors ES Cells
KOMP-Regeneron
Design Finished/Oligos Ordered Projects: VG16725

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
25 0 2 0 view in Ensembl

Atxn7l1os1

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn7l1os1 was found for the following reasons:
marker_name - ataxin 7-like 1, opposite strand 1
symbol - Atxn7l1os1
marker_symbol_str - Atxn7l1os1
marker_symbol - Atxn7l1os1

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

Atxn7l1os2

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn7l1os2 was found for the following reasons:
marker_name - ataxin 7-like 1, opposite strand 2
symbol - Atxn7l1os2
marker_symbol_str - Atxn7l1os2
marker_symbol - Atxn7l1os2

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources no data available

Atxn7l2

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn7l2 was found for the following reasons:
marker_name - ataxin 7-like 2
symbol - Atxn7l2
marker_symbol_str - Atxn7l2
marker_symbol - Atxn7l2

Gene Details no data available

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
16 5 1 0 view in Ensembl

Atxn7l3

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn7l3 was found for the following reasons:
colony_prefix - Atxn7l3
ikmc_project_product_status - KOMP-CSD Vector Available
marker_name - ataxin 7-like 3
symbol - Atxn7l3
targeting_vector - DPGS00142_A_C03
marker_symbol_str - Atxn7l3
marker_symbol - Atxn7l3
product_status - Vector Available
intermediate_vector - PCS00142_A_C03

Gene Details no data available

WTSI Phenotyping no data available

IKMC Vectors and ES Cells no data available

DNA Clone Resources

C57Bl/6J Bacs 129 Bacs MICER clones KO Targeting Vectors
10 6 3 0 view in Ensembl

Atxn7l3b

Datasets: Gene Details WTSI Phenotyping Mice IKMC Vectors and ES Cells DNA Clone Resources
Atxn7l3b was found for the following reasons:
synonym - AI315132
ikmc_project_product_status - TIGM ES Cell Available
marker_name - ataxin 7-like 3B
symbol - Atxn7l3b
marker_symbol_str - Atxn7l3b
marker_symbol - Atxn7l3b
product_status - ES Cell Available

Gene Details

Marker Name(s): ataxin 7-like 3B
view this gene in MGI
Marker Type: protein coding gene
Synonyms: 4921506J03Rik, 6230409E21Rik, AI315132, ENSMUSG00000074747
Location: Chr10:112925430-112929001(-)
Related Human Conditions (from OMIM) - no related Human Condition
More Information
MGI Gene Accession: MGI:1914971 Ensembl Gene ID: ENSMUSG00000074748 Vega Gene ID: OTTMUSG00000035375
Entrez Gene ID: 382423 CCDS ID:
Orthologs / Homologs
Species Marker Symbol Entrez Gene ID Ensembl Gene ID
Human ATXN7L3B 552889
Rat Atxn7l3b 100192313

WTSI Phenotyping no data available

Mice no data available

IKMC Vectors and ES Cells

Vectors ES Cells
EUCOMM
Vector Construction in Progress Projects: 97459
Vectors ES Cells
KOMP-Regeneron
Targeting Vector QC Completed Projects: VG12865

DNA Clone Resources no data available