Project on Canine Transmissible Tumour Worldwide Distribution

Cancer Genome Project, Department of Veterinary Medicine, University of Cambridge

CTVT (also known as Sticker's Sarcoma, Infective Venereal Tumour, TVT, Venereal Sarcoma) is a common disease of dogs and is found worldwide. Primary tumours occur on the external genitalia of both sexes and the disease is usually transmitted during mating.

The aim of the research project is to collect data on worldwide prevalence of CTVT, which will help us to identify any CTVT risk factors and therefore possible CTVT prevention. In addition to filling a questionnaire, we would like to invite you to participate in research collaboration by collecting samples and have the opportunity to win a trip to Cambridge. Collection of samples will be used for a genetics study of transmissible cancers and the evolutionary processes which have permitted their emergence and spread.

All the data will be kept confidential. Your contribution to this project is much appreciated!

For further information about the CTVT project contact:

Andrea Strakova
Department of Veterinary Medicine
University of Cambridge
as2112@cam.ac.uk

Dr Elizabeth Murchison
Department of Veterinary Medicine
Cancer Genome Project
Wellcome Trust Sanger Institute
epm27@cam.ac.uk

Your information

Name: Required
Email address: Required
Country: Required
Town: Required
Organisation type
Organisation type (other)
Number of dogs in your area:
Most dogs in my area are:
If you have extra information, please, comment:
Is there a noticeable population of free-roaming dogs in your area?
If you have extra information, please, comment:

Questionnaire

Have you ever seen a case of CTVT in your clinic?
What is your opinion on prevalence (% of affected dogs) of CTVT in your region?
If you have more precise data, please comment
How many CTVT cases do you see per year?
Most of my CTVT cases are from:
Have you observed CTVT in other regions of your country or the world?
Is it noticeably absent from any region in your country?
How often does metastasis occur in the cases you have observed?
What other parts of the body, apart from genitalia, (e.g. skin, lymph nodes) are affected?
Have you ever observed spontaneous regression of tumours (without treatment)?
If yes, please provide details (sex, age, location of the primary tumour, size of the tumour, timeline of the tumour regression

Treatments used

Information: Treatment used (tick all that apply)
Vincristine
Doxorubicine
Radiotherapy
Surgery
No treatment
Other
If 'other' or more choices ticked, please specify
What proportion of tumours goes into complete remission after using the selected treatment?
Gender of the majority of affected dogs
Comment on percentage of predominant sex
Most of dogs with CTVT are:
If diseased, what is the most frequent disease/parasite in dogs with CTVT?
What is the most common disease/parasite in your practice?
Comment on any unusual cases of CTVT that you have seen
Have you ever come across CTVT in other species (e.g. fox, wolf, coyote, jackal)?
Any other comments
Have you got any PHOTOGRAPHS you could send me?: My email address: ctvt@sanger.ac.uk
Is there a national veterinary organisation in your country?
If yes, what is its name/contact?
WOULD YOU LIKE TO TAKE PART IN RESEARCH COLLABORATION?: Required
All materials required for sampling as well as postage are paid for by us. The Ethics Review Committee (ERC) of The Wellcome Trust Sanger Institute officially approves the collection and use of animal tissues for this study and is happy for me to notify this approval to all veterinarians and veterinary organisations involved in collecting samples.
I would like to receive emails about the project in the future: Required