New genetic analysis reveals late spread of breast cancer and backs key role of early diagnosis
Mystery epidemic that crossed species in Iceland is solved
The bacteria behind a nationwide epidemic of a mysterious respiratory disease in Icelandic ponies has been identified by scientists at the Wellcome Trust Sanger Institute and their collaborators. The team tracked the bug back to its source: a water treadmill used by horses in rehabilitation.
Present-day Lebanese descend from Biblical Canaanites, genetic study suggests
In the most recent whole-genome study of ancient remains from the Near East, Wellcome Trust Sanger Institute scientists and their collaborators sequenced the entire genomes of 4,000-year-old Canaanite individuals who inhabited the region during the Bronze Age, and compared these to other ancient and present-day populations. The results, published today (27 July) in the American Journal of Human Genetics suggest that present-day Lebanese are direct descendants of the ancient Canaanites.
Contact the Press Office
Dr Samantha Wynne
Wellcome Trust Sanger Institute,
Tel +44 (0)1223 492 368
Mobile +44 (0) 7900 607793
Fax +44 (0)1223 494 919
The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.
Developmental cell 2017;42;3;241-255.e6
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
Delineating the phenotypic spectrum of Bainbridge-Ropers syndrome: 12 new patients with de novo, heterozygous, loss-of-function mutations in ASXL3 and review of published literature.
Journal of medical genetics 2017
Epigenetic germline inheritance in mammals: Looking to the past to understand the future.
Genes, brain, and behavior 2017
Morphology, topology and dimensions of the heart and arteries of genetically normal and mutant mouse embryos at stages S21-S23.
Journal of anatomy 2017
Circulating and Tissue-resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function is Altered During Inflammation.
Molecular epidemiology of Klebsiella pneumoniae invasive infections over a decade at Kilifi County Hospital in Kenya.
International journal of medical microbiology : IJMM 2017
Nature reviews. Microbiology 2017
Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries.
Scientific reports 2017;7;1;7384
Human Germline Genome Editing.
American journal of human genetics 2017;101;2;167-176
NBEAL2 is required for neutrophil and NK cell function and pathogen defense.
The Journal of clinical investigation 2017